biostudies-literatureUnknown29(1)Wilkinson RL<h4>Background</h4>Postinjury pain is a well-known debilitating complication of spinal cord injury (SCI), often resulting in long-term, high-dose opioid use with the potential for dependence. There is a gap in knowledge about the risk of opioid dependence and the associated health care utilization and cost in SCI.<h4>Objectives</h4>To evaluate the association of SCI with postinjury opioid use and dependence and evaluate the effect of this opioid dependence on postinjury health care utilization.<h4>Methods</h4>Using the MarketScan Database, health care utilization claims data were queried to extract 7187 adults with traumatic SCI from 2000 to 2019. Factors associated with post-SCI opioid use and dependence, postinjury health care utilization, and payments were analyzed with generalized lineTopics in spinal cord injury rehabilitation118-130https://www.ebi.ac.uk/biostudies/studies/S-EPMC9936895biostudies-literatureOpioid Dependence and Associated Health Care Utilization and Cost in Traumatic Spinal Cord Injury Population: Analysis Using Marketscan Database.PMC9936895Herrity AUgiliweneza BBoakye MAdams SDrazin DKhattar NWang DWilkinson RLCastillo CNuno MSharma MDietz NfalseOpioid Dependence and Associated Health Care Utilization and Cost in Traumatic Spinal Cord Injury Population: Analysis Using Marketscan Database.<h4>Background</h4>Postinjury pain is a well-known debilitating complication of spinal cord injury (SCI), often resulting in long-term, high-dose opioid use with the potential for dependence. There is a gap in knowledge about the risk of opioid dependence and the associated health care utilization and cost in SCI.<h4>Objectives</h4>To evaluate the association of SCI with postinjury opioid use and dependence and evaluate the effect of this opioid dependence on postinjury health care utilization.<h4>Methods</h4>Using the MarketScan Database, health care utilization claims data were queried to extract 7187 adults with traumatic SCI from 2000 to 2019. Factors associated with post-SCI opioid use and dependence, postinjury health care utilization, and payments were analyzed with generalized line2023-01-01T00:00:00Z20232025-04-05T15:54:17.363Z2025-04-05T15:54:17.363ZS-EPMC99368953681992710.46292/sci22-00026