{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Webb CA"],"funding":["NCCIH NIH HHS","NIDA NIH HHS","NIMH NIH HHS","U.S. Department of Health & Human Services | NIH | National Center for Complementary and Integrative Health","U.S. Department of Health & Human Services | NIH | National Institute of Mental Health"],"pagination":["623-632"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9938220"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["48(4)"],"pubmed_abstract":["Anhedonia is a cardinal characteristic of depression which predicts worse treatment outcome and is among the most common residual symptoms following treatment. Behavioral Activation (BA) has been shown to be an effective treatment for depressed adults, and more recently, depressed adolescents. Given its emphasis on systematically and gradually increasing exposure to and engagement with rewarding activities and experiences, BA may be a particularly effective intervention for adolescents experiencing anhedonia and associated reward system dysfunction. In the present study, anhedonic adolescents (AA; n = 39) received 12 weekly sessions of BA and completed a multimodal (i.e., neural, behavioral, and self-report [ecological momentary assessment]) assessment of reward function at pre-treatment a"],"journal":["Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology"],"pubmed_title":["Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: a multimodal approach."],"pmcid":["PMC9938220"],"funding_grant_id":["R01MH116969","T32 DA015036","R01AT011002","K23MH108752","R01 MH104418","K23 MH108752","R01 MH116969","R37 MH068376","R01 MH124900","R01 AT011002"],"pubmed_authors":["Forbes EE","Webb CA","Pizzagalli DA","Murray L","Tierney AO"],"additional_accession":[]},"is_claimable":false,"name":"Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: a multimodal approach.","description":"Anhedonia is a cardinal characteristic of depression which predicts worse treatment outcome and is among the most common residual symptoms following treatment. Behavioral Activation (BA) has been shown to be an effective treatment for depressed adults, and more recently, depressed adolescents. Given its emphasis on systematically and gradually increasing exposure to and engagement with rewarding activities and experiences, BA may be a particularly effective intervention for adolescents experiencing anhedonia and associated reward system dysfunction. In the present study, anhedonic adolescents (AA; n = 39) received 12 weekly sessions of BA and completed a multimodal (i.e., neural, behavioral, and self-report [ecological momentary assessment]) assessment of reward function at pre-treatment a","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2026-07-14T22:11:23.755Z","creation":"2025-04-04T20:40:15.843Z"},"accession":"S-EPMC9938220","cross_references":{"pubmed":["36307561"],"doi":["10.1038/s41386-022-01481-4"]}}