{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Zhao FY"],"funding":["National Key Research and Development Program of China","RMIT University"],"pubmed_abstract":["<h4>Background and objective</h4>Whilst acupuncture is widely used for treating psychosomatic diseases, there is little high-quality evidence supporting its application in comorbid perimenopausal depression (PMD) and insomnia (PMI) which are common complaints during climacteric. This feasibility, patient-assessor-blinded, randomized, sham-controlled clinical trial addresses this gap by investigating the efficacy and safety of acupuncture on depressed mood and poor sleep in women with comorbid PMD and PMI.<h4>Methods</h4>Seventy eligible participants were randomly assigned to either real-acupuncture (RA) or sham-acupuncture (SA) groups. Either RA or SA treatment were delivered in 17 sessions over 8 weeks. The primary outcomes for mood and sleep were changes on 17-items Hamilton Depression R"],"journal":["Frontiers in public health"],"pagination":["1120567"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9939459"],"repository":["biostudies-literature"],"pubmed_title":["Acupuncture for comorbid depression and insomnia in perimenopause: A feasibility patient-assessor-blinded, randomized, and sham-controlled clinical trial."],"pmcid":["PMC9939459"],"pubmed_authors":["Zheng Z","Fu QQ","Zhang WJ","Zhao FY","Wang HR","Huang YL","Jiang T","Xu H","Kennedy GA","Conduit R"],"additional_accession":[]},"is_claimable":false,"name":"Acupuncture for comorbid depression and insomnia in perimenopause: A feasibility patient-assessor-blinded, randomized, and sham-controlled clinical trial.","description":"<h4>Background and objective</h4>Whilst acupuncture is widely used for treating psychosomatic diseases, there is little high-quality evidence supporting its application in comorbid perimenopausal depression (PMD) and insomnia (PMI) which are common complaints during climacteric. This feasibility, patient-assessor-blinded, randomized, sham-controlled clinical trial addresses this gap by investigating the efficacy and safety of acupuncture on depressed mood and poor sleep in women with comorbid PMD and PMI.<h4>Methods</h4>Seventy eligible participants were randomly assigned to either real-acupuncture (RA) or sham-acupuncture (SA) groups. Either RA or SA treatment were delivered in 17 sessions over 8 weeks. The primary outcomes for mood and sleep were changes on 17-items Hamilton Depression R","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-04T20:10:19.82Z","creation":"2025-04-04T20:10:19.82Z"},"accession":"S-EPMC9939459","cross_references":{"pubmed":["36815166"],"doi":["10.3389/fpubh.2023.1120567"]}}