biostudies-literatureNikl ACorvinus University of BudapestMinistry of Innovation and Technology in HungaryNew National Excellence Program of the Ministry for Innovation and TechnologyJános Bolyai Research Scholarship of the Hungarian Academy of Sciences17https://www.ebi.ac.uk/biostudies/studies/S-EPMC9940337biostudies-literatureUnknown21(1)<h4>Background</h4>The EQ-5D-5L and 15D are generic preference-accompanied health status measures with similar dimensions. In this study, we aim to compare the measurement properties of the EQ-5D-5L and 15D descriptive systems and index values in a general population sample.<h4>Methods</h4>In August 2021, an online cross-sectional survey was conducted in a representative adult general population sample (n = 1887). The EQ-5D-5L and 15D descriptive systems and index values were compared in terms of ceiling and floor, informativity (Shannon's Evenness index), agreement, convergent and known-groups validity for 41 chronic physical and mental health conditions. Danish value sets were used to compute index values for both instruments. As a sensitivity analysis, index values were also estimated uHealth and quality of life outcomesA head-to-head comparison of the EQ-5D-5L and 15D descriptive systems and index values in a general population sample.PMC9940337TKP2020-IKA-02ÚNKP-22-5-CORVINUS-4BO/00304/21Brodszky VJanssen MFRencz FNikl AfalseA head-to-head comparison of the EQ-5D-5L and 15D descriptive systems and index values in a general population sample.<h4>Background</h4>The EQ-5D-5L and 15D are generic preference-accompanied health status measures with similar dimensions. In this study, we aim to compare the measurement properties of the EQ-5D-5L and 15D descriptive systems and index values in a general population sample.<h4>Methods</h4>In August 2021, an online cross-sectional survey was conducted in a representative adult general population sample (n = 1887). The EQ-5D-5L and 15D descriptive systems and index values were compared in terms of ceiling and floor, informativity (Shannon's Evenness index), agreement, convergent and known-groups validity for 41 chronic physical and mental health conditions. Danish value sets were used to compute index values for both instruments. As a sensitivity analysis, index values were also estimated u2023-01-01T00:00:00Z2023 Feb2026-06-03T18:30:04.43Z2025-04-06T10:12:44.974ZS-EPMC99403373680386610.1186/s12955-023-02096-z