{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhu HB"],"funding":["Natural Science Foundation of Beijing Municipality","Beijing Hospitals Authority'Ascent Plan","National Nature Science Foundation of China","Beijing Hospitals Authority’Ascent Plan"],"pagination":["18"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9942330"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>Patients with colorectal liver metastases (CRLM) combined with hepatic lymph node (HLN) metastases have a poor prognosis. In this study, we developed and validated a model using clinical and magnetic resonance imaging (MRI) parameters to predict HLN status before surgery.<h4>Methods</h4>A total of 104 CRLM patients undergoing hepatic lymphonodectomy with pathologically confirmed HLN status after preoperative chemotherapy were enrolled in this study. The patients were further divided into a training group (n = 52) and a validation group (n = 52). The apparent diffusion coefficient (ADC) values, including ADC<sub>mean</sub> and ADC<sub>min</sub> of the largest HLN before and after treatment, were measured. rADC was calculated referring to the target liver metastases, splee"],"journal":["Cancer imaging : the official publication of the International Cancer Imaging Society"],"pubmed_title":["Prediction of hepatic lymph node metastases based on magnetic resonance imaging before and after preoperative chemotherapy in patients with colorectal liver metastases underwent surgical resection."],"pmcid":["PMC9942330"],"funding_grant_id":["DFL20191103","81874143, 31971192","Z200015, 7192035"],"pubmed_authors":["Zhu HB","Li XT","Zhang XY","Sun XF","Xu D","Xing BC","Sun YS","Wang K"],"additional_accession":[]},"is_claimable":false,"name":"Prediction of hepatic lymph node metastases based on magnetic resonance imaging before and after preoperative chemotherapy in patients with colorectal liver metastases underwent surgical resection.","description":"<h4>Background</h4>Patients with colorectal liver metastases (CRLM) combined with hepatic lymph node (HLN) metastases have a poor prognosis. In this study, we developed and validated a model using clinical and magnetic resonance imaging (MRI) parameters to predict HLN status before surgery.<h4>Methods</h4>A total of 104 CRLM patients undergoing hepatic lymphonodectomy with pathologically confirmed HLN status after preoperative chemotherapy were enrolled in this study. The patients were further divided into a training group (n = 52) and a validation group (n = 52). The apparent diffusion coefficient (ADC) values, including ADC<sub>mean</sub> and ADC<sub>min</sub> of the largest HLN before and after treatment, were measured. rADC was calculated referring to the target liver metastases, splee","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-18T14:11:37.949Z","creation":"2025-02-18T22:56:22.046Z"},"accession":"S-EPMC9942330","cross_references":{"pubmed":["36810192"],"doi":["10.1186/s40644-023-00529-y"]}}