biostudies-literatureZhu HBNatural Science Foundation of Beijing MunicipalityBeijing Hospitals Authority'Ascent PlanNational Nature Science Foundation of ChinaBeijing Hospitals Authority’Ascent Plan18https://www.ebi.ac.uk/biostudies/studies/S-EPMC9942330biostudies-literatureUnknown23(1)<h4>Background</h4>Patients with colorectal liver metastases (CRLM) combined with hepatic lymph node (HLN) metastases have a poor prognosis. In this study, we developed and validated a model using clinical and magnetic resonance imaging (MRI) parameters to predict HLN status before surgery.<h4>Methods</h4>A total of 104 CRLM patients undergoing hepatic lymphonodectomy with pathologically confirmed HLN status after preoperative chemotherapy were enrolled in this study. The patients were further divided into a training group (n = 52) and a validation group (n = 52). The apparent diffusion coefficient (ADC) values, including ADC_mean and ADC_min of the largest HLN before and after treatment, were measured. rADC was calculated referring to the target liver metastases, spleeCancer imaging : the official publication of the International Cancer Imaging SocietyPrediction of hepatic lymph node metastases based on magnetic resonance imaging before and after preoperative chemotherapy in patients with colorectal liver metastases underwent surgical resection.PMC9942330DFL2019110381874143, 31971192Z200015, 7192035Zhu HBLi XTZhang XYSun XFXu DXing BCSun YSWang KfalsePrediction of hepatic lymph node metastases based on magnetic resonance imaging before and after preoperative chemotherapy in patients with colorectal liver metastases underwent surgical resection.<h4>Background</h4>Patients with colorectal liver metastases (CRLM) combined with hepatic lymph node (HLN) metastases have a poor prognosis. In this study, we developed and validated a model using clinical and magnetic resonance imaging (MRI) parameters to predict HLN status before surgery.<h4>Methods</h4>A total of 104 CRLM patients undergoing hepatic lymphonodectomy with pathologically confirmed HLN status after preoperative chemotherapy were enrolled in this study. The patients were further divided into a training group (n = 52) and a validation group (n = 52). The apparent diffusion coefficient (ADC) values, including ADC_mean and ADC_min of the largest HLN before and after treatment, were measured. rADC was calculated referring to the target liver metastases, splee2023-01-01T00:00:00Z2023 Feb2025-04-18T14:11:37.949Z2025-02-18T22:56:22.046ZS-EPMC99423303681019210.1186/s40644-023-00529-y