{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(2)"],"submitter":["Xu N"],"pubmed_abstract":["<h4>Background</h4>This study aims to evaluate the efficacy of the standard agglutination test (SAT), the Brucellacapt test and enzyme-linked immunosorbent assay (ELISA) in clinical specimens collected from patients with suspected brucellosis.<h4>Methods</h4>A prospective study was conducted from December 2020 to December 2021. Brucellosis was diagnosed on the basis of clinical evidence, and confirmed by isolation of Brucella or a four-fold rise in SAT titer. All samples were tested by the SAT, ELISA and the Brucellacapt test. Titers ≥1:100 were considered as SAT positive; ELISA was considered positive when an index greater than 11 was detected, while titers ≥1/160 indicated positivity on the Brucellacapt test. The specificity, sensitivity, and positive (PPVs) and negative predictive value"],"journal":["PLoS neglected tropical diseases"],"pagination":["e0011131"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9942959"],"repository":["biostudies-literature"],"pubmed_title":["Evaluating the efficacy of serological testing of clinical specimens collected from patients with suspected brucellosis."],"pmcid":["PMC9942959"],"pubmed_authors":["Yang H","Liu H","Qu C","Xu N","Yang L","Wang S","Sai L","Wen S","Wang G"],"additional_accession":[]},"is_claimable":false,"name":"Evaluating the efficacy of serological testing of clinical specimens collected from patients with suspected brucellosis.","description":"<h4>Background</h4>This study aims to evaluate the efficacy of the standard agglutination test (SAT), the Brucellacapt test and enzyme-linked immunosorbent assay (ELISA) in clinical specimens collected from patients with suspected brucellosis.<h4>Methods</h4>A prospective study was conducted from December 2020 to December 2021. Brucellosis was diagnosed on the basis of clinical evidence, and confirmed by isolation of Brucella or a four-fold rise in SAT titer. All samples were tested by the SAT, ELISA and the Brucellacapt test. Titers ≥1:100 were considered as SAT positive; ELISA was considered positive when an index greater than 11 was detected, while titers ≥1/160 indicated positivity on the Brucellacapt test. The specificity, sensitivity, and positive (PPVs) and negative predictive value","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-18T14:11:34.725Z","creation":"2025-02-18T22:55:21.04Z"},"accession":"S-EPMC9942959","cross_references":{"pubmed":["36802393"],"doi":["10.1371/journal.pntd.0011131"]}}