{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Miller JR"],"funding":["NIA NIH HHS","Columbia University Medical Center","NINDS NIH HHS","The University of Texas Southwestern Medical Center"],"pagination":["16-20"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9943057"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["98"],"pubmed_abstract":["<h4>Introduction</h4>Essential tremor (ET), a common movement disorder, is characterized by motor, cognitive and psychiatric symptoms. Depressed mood, a symptom of ET, has historically been viewed as a psychological response to disability. However, depressive symptoms are emerging as a predictor of cognitive decline across several clinical populations. We examined if depressive symptoms predict decline in global cognition, memory, and executive functioning among older adults with ET.<h4>Methods</h4>125 cognitively normal participants with ET completed three in-person assessments of cognition, mood, and motor symptoms at baseline, 18 months, and 36 months; baseline data were collected from July 2014-July 2016. Depressive symptoms were measured with the Geriatric Depression Scale. Cognitive "],"journal":["Parkinsonism & related disorders"],"pubmed_title":["Depressive symptoms predict memory decline in Essential Tremor."],"pmcid":["PMC9943057"],"funding_grant_id":["P30 AG066462","R01 NS086736","R01 AG034618"],"pubmed_authors":["Delgado N","Huey ED","Louis ED","Chapman S","Hernandez DI","Cosentino S","Radler K","Miller JR"],"additional_accession":[]},"is_claimable":false,"name":"Depressive symptoms predict memory decline in Essential Tremor.","description":"<h4>Introduction</h4>Essential tremor (ET), a common movement disorder, is characterized by motor, cognitive and psychiatric symptoms. Depressed mood, a symptom of ET, has historically been viewed as a psychological response to disability. However, depressive symptoms are emerging as a predictor of cognitive decline across several clinical populations. We examined if depressive symptoms predict decline in global cognition, memory, and executive functioning among older adults with ET.<h4>Methods</h4>125 cognitively normal participants with ET completed three in-person assessments of cognition, mood, and motor symptoms at baseline, 18 months, and 36 months; baseline data were collected from July 2014-July 2016. Depressive symptoms were measured with the Geriatric Depression Scale. Cognitive ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-22T09:52:39.558Z","creation":"2025-02-18T22:53:27.034Z"},"accession":"S-EPMC9943057","cross_references":{"pubmed":["35421780"],"doi":["10.1016/j.parkreldis.2022.03.013"]}}