biostudies-literatureMiller JRNIA NIH HHSColumbia University Medical CenterNINDS NIH HHSThe University of Texas Southwestern Medical Center16-20https://www.ebi.ac.uk/biostudies/studies/S-EPMC9943057biostudies-literatureUnknown98<h4>Introduction</h4>Essential tremor (ET), a common movement disorder, is characterized by motor, cognitive and psychiatric symptoms. Depressed mood, a symptom of ET, has historically been viewed as a psychological response to disability. However, depressive symptoms are emerging as a predictor of cognitive decline across several clinical populations. We examined if depressive symptoms predict decline in global cognition, memory, and executive functioning among older adults with ET.<h4>Methods</h4>125 cognitively normal participants with ET completed three in-person assessments of cognition, mood, and motor symptoms at baseline, 18 months, and 36 months; baseline data were collected from July 2014-July 2016. Depressive symptoms were measured with the Geriatric Depression Scale. Cognitive Parkinsonism & related disordersDepressive symptoms predict memory decline in Essential Tremor.PMC9943057P30 AG066462R01 NS086736R01 AG034618Delgado NHuey EDLouis EDChapman SHernandez DICosentino SRadler KMiller JRfalseDepressive symptoms predict memory decline in Essential Tremor.<h4>Introduction</h4>Essential tremor (ET), a common movement disorder, is characterized by motor, cognitive and psychiatric symptoms. Depressed mood, a symptom of ET, has historically been viewed as a psychological response to disability. However, depressive symptoms are emerging as a predictor of cognitive decline across several clinical populations. We examined if depressive symptoms predict decline in global cognition, memory, and executive functioning among older adults with ET.<h4>Methods</h4>125 cognitively normal participants with ET completed three in-person assessments of cognition, mood, and motor symptoms at baseline, 18 months, and 36 months; baseline data were collected from July 2014-July 2016. Depressive symptoms were measured with the Geriatric Depression Scale. Cognitive 2022-01-01T00:00:00Z2022 May2025-04-22T09:52:39.558Z2025-02-18T22:53:27.034ZS-EPMC99430573542178010.1016/j.parkreldis.2022.03.013