biostudies-literatureGuan Lthe Hubei Chen Xiaoping Technology Development Fund44https://www.ebi.ac.uk/biostudies/studies/S-EPMC9945388biostudies-literatureUnknown23(1)<h4>Background</h4>Appendicitis is the most common abdominal surgical emergency worldwide, and its burden has been changing. We report the level and trends of appendicitis prevalence, and incidence; and years lived with disability (YLD) in 204 countries and territories from 1990 to 2019, based on data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019.<h4>Methods</h4>The numbers and age-standardized prevalence, incidence, and YLD rates per 100,000 population of appendicitis were estimated across regions and countries by age, sex, and sociodemographic index (SDI). All the estimates were reported with 95% uncertainty intervals (UIs).<h4>Results</h4>Globally, the age-standardized prevalence and incidence rates of appendicitis in 2019 were 8.7 (95% UI 6.9 to 11.0) BMC gastroenterologyThe global, regional, and national burden of appendicitis in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019.PMC9945388CXPJJH1190000-2019321Guan LPan GLiu ZOuyang GZhang BWu YGan TfalseThe global, regional, and national burden of appendicitis in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019.<h4>Background</h4>Appendicitis is the most common abdominal surgical emergency worldwide, and its burden has been changing. We report the level and trends of appendicitis prevalence, and incidence; and years lived with disability (YLD) in 204 countries and territories from 1990 to 2019, based on data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019.<h4>Methods</h4>The numbers and age-standardized prevalence, incidence, and YLD rates per 100,000 population of appendicitis were estimated across regions and countries by age, sex, and sociodemographic index (SDI). All the estimates were reported with 95% uncertainty intervals (UIs).<h4>Results</h4>Globally, the age-standardized prevalence and incidence rates of appendicitis in 2019 were 8.7 (95% UI 6.9 to 11.0) 2023-01-01T00:00:00Z2023 Feb2025-04-19T00:56:16.778Z2025-04-07T11:57:08.085ZS-EPMC99453883681419010.1186/s12876-023-02678-7