{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["64(2)"],"submitter":["Loewinger AS"],"pubmed_abstract":["<h4>Purpose</h4>To quantify choriocapillaris flow alterations in patients with pseudoxanthoma elasticum (PXE) in pre-atrophic stages and its association with structural changes of the choroid and outer retina.<h4>Methods</h4>Thirty-two eyes of 21 patients with PXE and 35 healthy eyes of 35 controls were included. The density of choriocapillaris flow signal deficits (FDs) was quantified on 6 × 6-mm optical coherence tomography angiography (OCTA) images. Spectral-domain optical coherence tomography (SD-OCT) images were analyzed for thicknesses of the choroid and outer retinal microstructure and correlated with choriocapillaris FDs in the respective Early Treatment Diabetic Retinopathy Study subfield.<h4>Results</h4>The multivariable mixed model analysis for choriocapillaris FDs revealed sign"],"journal":["Investigative ophthalmology & visual science"],"pagination":["21"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9946047"],"repository":["biostudies-literature"],"pubmed_title":["Choriocapillaris Flow Signal Impairment in Patients With Pseudoxanthoma Elasticum."],"pmcid":["PMC9946047"],"pubmed_authors":["Loewinger AS","Holz FG","Pfau M","Pfau K","Herrmann P"],"additional_accession":[]},"is_claimable":false,"name":"Choriocapillaris Flow Signal Impairment in Patients With Pseudoxanthoma Elasticum.","description":"<h4>Purpose</h4>To quantify choriocapillaris flow alterations in patients with pseudoxanthoma elasticum (PXE) in pre-atrophic stages and its association with structural changes of the choroid and outer retina.<h4>Methods</h4>Thirty-two eyes of 21 patients with PXE and 35 healthy eyes of 35 controls were included. The density of choriocapillaris flow signal deficits (FDs) was quantified on 6 × 6-mm optical coherence tomography angiography (OCTA) images. Spectral-domain optical coherence tomography (SD-OCT) images were analyzed for thicknesses of the choroid and outer retinal microstructure and correlated with choriocapillaris FDs in the respective Early Treatment Diabetic Retinopathy Study subfield.<h4>Results</h4>The multivariable mixed model analysis for choriocapillaris FDs revealed sign","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-05-28T17:46:47.316Z","creation":"2025-04-04T11:27:08.783Z"},"accession":"S-EPMC9946047","cross_references":{"pubmed":["36809302"],"doi":["10.1167/iovs.64.2.21"]}}