{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["150"],"submitter":["Eberhardt AT"],"pubmed_abstract":["The SARS-CoV-2 Omicron variant has increased infectivity and immune escape compared with previous variants, and caused the surge of massive COVID-19 waves globally. Despite a vast majority (~90%) of the population of Santa Fe city, Argentina had been vaccinated and/or had been infected by SARS-CoV-2 when Omicron emerged, the epidemic wave that followed its arrival was by far the largest one experienced in the city. A serosurvey conducted prior to the arrival of Omicron allowed to assess the acquired humoral defences preceding the wave and to conduct a longitudinal study to provide individual-level real-world data linking antibody levels and protection against COVID-19 during the wave. A very large proportion of 1455 sampled individuals had immunological memory against COVID-19 at the arriv"],"journal":["Epidemiology and infection"],"pagination":["e187"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9947048"],"repository":["biostudies-literature"],"pubmed_title":["Preceding anti-spike IgG levels predicted risk and severity of COVID-19 during the Omicron-dominant wave in Santa Fe city, Argentina."],"pmcid":["PMC9947048"],"pubmed_authors":["Simoncini M","Viotto E","Galoppo G","Pina C","Sklar D","Marignac V","Racca A","Junges C","Genolet A","Botto C","Palavecino C","Eberhardt AT","Parachu-Marco V","Valli F","Beccaria C","Fernandez H","Munoz de Toro M","Mingo G","Armando G","Bossio JC","Aimar H","Beldomenico PM","Scarpa L","Arce S","Facelli F"],"additional_accession":[]},"is_claimable":false,"name":"Preceding anti-spike IgG levels predicted risk and severity of COVID-19 during the Omicron-dominant wave in Santa Fe city, Argentina.","description":"The SARS-CoV-2 Omicron variant has increased infectivity and immune escape compared with previous variants, and caused the surge of massive COVID-19 waves globally. Despite a vast majority (~90%) of the population of Santa Fe city, Argentina had been vaccinated and/or had been infected by SARS-CoV-2 when Omicron emerged, the epidemic wave that followed its arrival was by far the largest one experienced in the city. A serosurvey conducted prior to the arrival of Omicron allowed to assess the acquired humoral defences preceding the wave and to conduct a longitudinal study to provide individual-level real-world data linking antibody levels and protection against COVID-19 during the wave. A very large proportion of 1455 sampled individuals had immunological memory against COVID-19 at the arriv","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-21T16:10:22.582Z","creation":"2025-04-21T16:10:22.582Z"},"accession":"S-EPMC9947048","cross_references":{"pubmed":["36325837"],"doi":["10.1017/S0950268822001716"]}}