{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17"],"submitter":["Wang Y"],"pubmed_abstract":["<h4>Introduction</h4>The loss of the neural sensory function pathways between the stump limbs and the brain greatly impacts the rehabilitation of limb function and the daily lives of amputees. Non-invasive physical stressors, such as mechanical pressure and transcutaneous electrical nerve stimulation (TENS), could be potential solutions for recovering somatic sensations in amputees. Previous studies have shown that stimulating the residual or regenerated nerves in the stumps of some amputees can produce phantom hand sensations. However, the results are inconclusive due to unstable physiological responses caused by inaccurate stimulus parameters and positions.<h4>Methods</h4>In this study, we developed an optimal TENS strategy by mapping the distribution of the nerves in the stump skin that"],"journal":["Frontiers in neuroscience"],"pagination":["1114962"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9947467"],"repository":["biostudies-literature"],"pubmed_title":["Electrical nerve stimulation for sensory-neural pathway reconstruction in upper-limb amputees."],"pmcid":["PMC9947467"],"pubmed_authors":["Liu H","Zhou L","Zeng P","Tao Y","Ji L","Wang Y","Zhou Y"],"additional_accession":[]},"is_claimable":false,"name":"Electrical nerve stimulation for sensory-neural pathway reconstruction in upper-limb amputees.","description":"<h4>Introduction</h4>The loss of the neural sensory function pathways between the stump limbs and the brain greatly impacts the rehabilitation of limb function and the daily lives of amputees. Non-invasive physical stressors, such as mechanical pressure and transcutaneous electrical nerve stimulation (TENS), could be potential solutions for recovering somatic sensations in amputees. Previous studies have shown that stimulating the residual or regenerated nerves in the stumps of some amputees can produce phantom hand sensations. However, the results are inconclusive due to unstable physiological responses caused by inaccurate stimulus parameters and positions.<h4>Methods</h4>In this study, we developed an optimal TENS strategy by mapping the distribution of the nerves in the stump skin that","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-29T10:48:00.785Z","creation":"2025-04-06T19:41:23.048Z"},"accession":"S-EPMC9947467","cross_references":{"pubmed":["36845418"],"doi":["10.3389/fnins.2023.1114962"]}}