biostudies-literatureLatimer KWNEI NIH HHSU.S. Department of DefenseNINDS NIH HHSU.S. Department of Health & Human Services | National Institutes of Health1010https://www.ebi.ac.uk/biostudies/studies/S-EPMC9950136biostudies-literatureUnknown14(1)Neurons in parietal cortex exhibit task-related activity during decision-making tasks. However, it remains unclear how long-term training to perform different tasks over months or even years shapes neural computations and representations. We examine lateral intraparietal area (LIP) responses during a visual motion delayed-match-to-category task. We consider two pairs of male macaque monkeys with different training histories: one trained only on the categorization task, and another first trained to perform fine motion-direction discrimination (i.e., pretrained). We introduce a novel analytical approach-generalized multilinear models-to quantify low-dimensional, task-relevant components in population activity. During the categorization task, we found stronger cosine-like motion-direction tunNature communicationsLow-dimensional encoding of decisions in parietal cortex reflects long-term training history.PMC9950136R01 EY019041VBFFEY019041U19 NS107609Freedman DJLatimer KWfalseLow-dimensional encoding of decisions in parietal cortex reflects long-term training history.Neurons in parietal cortex exhibit task-related activity during decision-making tasks. However, it remains unclear how long-term training to perform different tasks over months or even years shapes neural computations and representations. We examine lateral intraparietal area (LIP) responses during a visual motion delayed-match-to-category task. We consider two pairs of male macaque monkeys with different training histories: one trained only on the categorization task, and another first trained to perform fine motion-direction discrimination (i.e., pretrained). We introduce a novel analytical approach-generalized multilinear models-to quantify low-dimensional, task-relevant components in population activity. During the categorization task, we found stronger cosine-like motion-direction tun2023-01-01T00:00:00Z2023 Feb2025-04-04T20:17:25.108Z2025-04-04T20:17:25.108ZS-EPMC99501363682310910.1038/s41467-023-36554-5