biostudies-literatureRoca-Fernandez ANational Institute for Health Research (NIHR)European Commissione002241https://www.ebi.ac.uk/biostudies/studies/S-EPMC9950586biostudies-literatureUnknown10(1)<h4>Background</h4>Long COVID is associated with multiple symptoms and impairment in multiple organs. Cross-sectional studies have reported cardiac impairment to varying degrees by varying methodologies. Using cardiac MR (CMR), we investigated a 12-month trajectory of abnormalities in Long COVID.<h4>Objectives</h4>To investigate cardiac abnormalities 1-year post-SARS-CoV-2 infection.<h4>Methods</h4>534 individuals with Long COVID underwent CMR (T1/T2 mapping, cardiac mass, volumes, function and strain) and multiorgan MRI at 6 months (IQR 4.3-7.3) since first post-COVID-19 symptoms. 330 were rescanned at 12.6 (IQR 11.4-14.2) months if abnormal baseline findings were reported. Symptoms, questionnaires and blood samples were collected at both time points. CMR abnormalities were defined as ≥1 Open heartCardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection.PMC9950586719445COV-LT2-0043AMD-719445-8Roca-Fernandez AMonteiro DBanerjee RCarapella VBull SWamil MBorlotti ALip GYHRobson MNtusi NBanerjee ADennis ABrady MThomaides-Brears HTelford AKelly MHeightman MfalseCardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection.<h4>Background</h4>Long COVID is associated with multiple symptoms and impairment in multiple organs. Cross-sectional studies have reported cardiac impairment to varying degrees by varying methodologies. Using cardiac MR (CMR), we investigated a 12-month trajectory of abnormalities in Long COVID.<h4>Objectives</h4>To investigate cardiac abnormalities 1-year post-SARS-CoV-2 infection.<h4>Methods</h4>534 individuals with Long COVID underwent CMR (T1/T2 mapping, cardiac mass, volumes, function and strain) and multiorgan MRI at 6 months (IQR 4.3-7.3) since first post-COVID-19 symptoms. 330 were rescanned at 12.6 (IQR 11.4-14.2) months if abnormal baseline findings were reported. Symptoms, questionnaires and blood samples were collected at both time points. CMR abnormalities were defined as ≥1 2023-01-01T00:00:00Z2023 Feb2026-07-14T20:54:08.514Z2026-06-24T03:04:18.437ZS-EPMC99505863682281810.1136/openhrt-2022-002241