{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhao J"],"funding":["Capital's Funds for Health Improvement and Research of China","Natural Science Foundation of Xiamen City","Capital’s Funds for Health Improvement and Research of China"],"pagination":["19"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9950708"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(1)"],"pubmed_abstract":["<h4>Background</h4>Non-alcoholic steatohepatitis (NASH) had not yet been approved therapy. Electro-acupuncture (EA) has been reported to have potential efficacy. However, high-quality clinical evidence was still lacking.<h4>Methods</h4>NASH patients were randomized and allocated to either sham acupuncture (SA) or EA group in a 1:1 ratio, with the patient blinded. Each patient received 36 sessions of SA or EA treatment over 12 weeks, followed by additional 4 weeks. The primary outcome was the changes in relative liver fat content measured by magnetic resonance imaging proton density fat fraction (MRI-PDFF).<h4>Results</h4>A total of 60 patients were enrolled. From baseline to week 12, the reduction of relative liver fat content measured by MRI-PDFF in the EA group (- 33.6%, quantile range: "],"journal":["Chinese medicine"],"pubmed_title":["Electro-acupuncture reduced steatosis on MRI-PDFF in patients with non-alcoholic steatohepatitis: a randomized controlled pilot clinical trial."],"pmcid":["PMC9950708"],"funding_grant_id":["2022-1-2021","2022-2-20213","82130018"],"pubmed_authors":["Wu L","Li J","Cao D","Du Y","Tong X","Zhao X","Jia J","Zhang W","Ren H","Wang Q","Xu S","Ou X","Han C","Zhao J","Duan W","You H"],"additional_accession":[]},"is_claimable":false,"name":"Electro-acupuncture reduced steatosis on MRI-PDFF in patients with non-alcoholic steatohepatitis: a randomized controlled pilot clinical trial.","description":"<h4>Background</h4>Non-alcoholic steatohepatitis (NASH) had not yet been approved therapy. Electro-acupuncture (EA) has been reported to have potential efficacy. However, high-quality clinical evidence was still lacking.<h4>Methods</h4>NASH patients were randomized and allocated to either sham acupuncture (SA) or EA group in a 1:1 ratio, with the patient blinded. Each patient received 36 sessions of SA or EA treatment over 12 weeks, followed by additional 4 weeks. The primary outcome was the changes in relative liver fat content measured by magnetic resonance imaging proton density fat fraction (MRI-PDFF).<h4>Results</h4>A total of 60 patients were enrolled. From baseline to week 12, the reduction of relative liver fat content measured by MRI-PDFF in the EA group (- 33.6%, quantile range: ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-05T13:20:24.378Z","creation":"2025-02-18T23:58:02.017Z"},"accession":"S-EPMC9950708","cross_references":{"pubmed":["36829229"],"doi":["10.1186/s13020-023-00724-w"]}}