{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(4)"],"submitter":["Blaj S"],"pubmed_abstract":["<h4>Background</h4>Pseudomyxoma peritonei (PMP) is a rare peritoneal condition where mucus-secreting tumorous cells progressively produce a thick, gelatin-like substance. The prognosis of patients with PMP is determined by the degree of cellularity within the mucin (low-grade (LAMN) vs. high-grade (HAMN) histologic features) and by the extent of the disease.<h4>Methods</h4>Prognostic relevance of tumor markers CA19-9 and CEA, gender, Peritoneal Cancer Index (PCI), and completeness of cytoreduction (CC) after cytoreductive surgery were evaluated on 193 consecutive PMP patients, based on a retrospective analysis of prospectively gathered data from a German tertial referral center.<h4>Results</h4>We demonstrated that low PCI, CC0 status, low-grade histology, and female gender were independent"],"journal":["Cancers"],"pagination":["1326"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9954733"],"repository":["biostudies-literature"],"pubmed_title":["Prognostic Factors in Pseudomyxoma Peritonei with Emphasis on the Predictive Role of Peritoneal Cancer Index and Tumor Markers."],"pmcid":["PMC9954733"],"pubmed_authors":["Herzberg J","Dora D","Piso P","Szasz AM","Kodacsi R","Lohinai Z","Schlitt HJ","Herold Z","Baransi S","Blaj S","Hornung M","Slowik P","Werner JM","Acs M"],"additional_accession":[]},"is_claimable":false,"name":"Prognostic Factors in Pseudomyxoma Peritonei with Emphasis on the Predictive Role of Peritoneal Cancer Index and Tumor Markers.","description":"<h4>Background</h4>Pseudomyxoma peritonei (PMP) is a rare peritoneal condition where mucus-secreting tumorous cells progressively produce a thick, gelatin-like substance. The prognosis of patients with PMP is determined by the degree of cellularity within the mucin (low-grade (LAMN) vs. high-grade (HAMN) histologic features) and by the extent of the disease.<h4>Methods</h4>Prognostic relevance of tumor markers CA19-9 and CEA, gender, Peritoneal Cancer Index (PCI), and completeness of cytoreduction (CC) after cytoreductive surgery were evaluated on 193 consecutive PMP patients, based on a retrospective analysis of prospectively gathered data from a German tertial referral center.<h4>Results</h4>We demonstrated that low PCI, CC0 status, low-grade histology, and female gender were independent","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-26T02:54:36.676Z","creation":"2025-04-06T10:35:18.762Z"},"accession":"S-EPMC9954733","cross_references":{"pubmed":["36831667"],"doi":["10.3390/cancers15041326"]}}