biostudies-literatureUnknown15(4)Blaj S<h4>Background</h4>Pseudomyxoma peritonei (PMP) is a rare peritoneal condition where mucus-secreting tumorous cells progressively produce a thick, gelatin-like substance. The prognosis of patients with PMP is determined by the degree of cellularity within the mucin (low-grade (LAMN) vs. high-grade (HAMN) histologic features) and by the extent of the disease.<h4>Methods</h4>Prognostic relevance of tumor markers CA19-9 and CEA, gender, Peritoneal Cancer Index (PCI), and completeness of cytoreduction (CC) after cytoreductive surgery were evaluated on 193 consecutive PMP patients, based on a retrospective analysis of prospectively gathered data from a German tertial referral center.<h4>Results</h4>We demonstrated that low PCI, CC0 status, low-grade histology, and female gender were independentCancers1326https://www.ebi.ac.uk/biostudies/studies/S-EPMC9954733biostudies-literaturePrognostic Factors in Pseudomyxoma Peritonei with Emphasis on the Predictive Role of Peritoneal Cancer Index and Tumor Markers.PMC9954733Herzberg JDora DPiso PSzasz AMKodacsi RLohinai ZSchlitt HJHerold ZBaransi SBlaj SHornung MSlowik PWerner JMAcs MfalsePrognostic Factors in Pseudomyxoma Peritonei with Emphasis on the Predictive Role of Peritoneal Cancer Index and Tumor Markers.<h4>Background</h4>Pseudomyxoma peritonei (PMP) is a rare peritoneal condition where mucus-secreting tumorous cells progressively produce a thick, gelatin-like substance. The prognosis of patients with PMP is determined by the degree of cellularity within the mucin (low-grade (LAMN) vs. high-grade (HAMN) histologic features) and by the extent of the disease.<h4>Methods</h4>Prognostic relevance of tumor markers CA19-9 and CEA, gender, Peritoneal Cancer Index (PCI), and completeness of cytoreduction (CC) after cytoreductive surgery were evaluated on 193 consecutive PMP patients, based on a retrospective analysis of prospectively gathered data from a German tertial referral center.<h4>Results</h4>We demonstrated that low PCI, CC0 status, low-grade histology, and female gender were independent2023-01-01T00:00:00Z2023 Feb2025-04-26T02:54:36.676Z2025-04-06T10:35:18.762ZS-EPMC99547333683166710.3390/cancers15041326