{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Beauchamp G"],"funding":["National Institute of Allergy and Infectious Diseases","NIAID NIH HHS","NIMH NIH HHS"],"pagination":["e0281728"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9956790"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(2)"],"pubmed_abstract":["Background
African adolescent girls and young women (AGYW) represent a large proportion of new HIV infections, a priority population for pre-exposure prophylaxis (PrEP), but adherence remains a challenge. A reliable, valid readiness tool would help identify AGYW motivated to take PrEP who need adherence support.Methods
In the HPTN 082 open-label PrEP study (2016-2019), South African and Zimbabwean women ages 16-25 were administered an HIV prevention readiness measure (HPRM). The 25 items in the HPRM included medication beliefs, connection with care, disclosure of PrEP use, social support, and housing stability using a 5-point Likert scale. Exploratory factor analysis (EFA) using polychoric correlations, scale reliability, and predictive validity were performed on data from "],"journal":["PloS one"],"pubmed_title":["Development of a tool to assess HIV prevention readiness of adolescent girls and young women in HPTN 082 study."],"pmcid":["PMC9956790"],"funding_grant_id":["UM1 AI069436","UM1AI068619","UM1 AI068613","P30 MH123248","UM1-AI068613","UM1 AI068617","UM1 AI068619","UM1 AI069463","UM1-AI068617","U01 AI069436"],"pubmed_authors":["Donnell DJ","Mgodi N","Celum C","Dye BJ","Anderson PL","HPTN 082 study team","Hosek S","Chan KCG","Flaherty BP","Bekker LG","Beauchamp G","Delany-Moretlwe S"],"additional_accession":[]},"is_claimable":false,"name":"Development of a tool to assess HIV prevention readiness of adolescent girls and young women in HPTN 082 study.","description":"Background
African adolescent girls and young women (AGYW) represent a large proportion of new HIV infections, a priority population for pre-exposure prophylaxis (PrEP), but adherence remains a challenge. A reliable, valid readiness tool would help identify AGYW motivated to take PrEP who need adherence support.Methods
In the HPTN 082 open-label PrEP study (2016-2019), South African and Zimbabwean women ages 16-25 were administered an HIV prevention readiness measure (HPRM). The 25 items in the HPRM included medication beliefs, connection with care, disclosure of PrEP use, social support, and housing stability using a 5-point Likert scale. Exploratory factor analysis (EFA) using polychoric correlations, scale reliability, and predictive validity were performed on data from ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2026-05-29T05:29:59.044Z","creation":"2025-02-18T23:44:49.464Z"},"accession":"S-EPMC9956790","cross_references":{"pubmed":["36827440"],"doi":["10.1371/journal.pone.0281728"]}}