biostudies-literatureChang YMinistry of Health & Wel-fare, Republic of KoreaInstitute of Information & Communications Technology Planning & Evaluationthe Institute of Information & Communications Technology Planning & EvaluationNational Research Foundation of Korea340https://www.ebi.ac.uk/biostudies/studies/S-EPMC9960411biostudies-literatureUnknown13(2)Periodontitis and rheumatoid arthritis (RA) are inflammatory diseases that share many similarities. We aimed to investigate the associations of periodontitis and oral hygiene status and behaviors with RA in a nationwide general population cohort. Participants from the National Health Screening cohort database of Korea who underwent oral health screening by dentists between 2003 and 2004 were included. The occurrence of RA was analyzed according to the presence of periodontitis, oral health examination findings, and behaviors. Overall, 2,239,586 participants were included. During a median of 16.7 years, RA occurred in 27,029 (1.2%) participants. The risk for incident RA was higher when participants had periodontitis (hazard ratio (HR) 1.2, 95% confidence interval (CI), 1.08-1.24) and an incJournal of personalized medicineAssociation of Oral Health with Risk of Rheumatoid Arthritis: A Nationwide Cohort Study.PMC99604112022-0-006212021R1F1A1048113HI22C0736002021R1I1A1A01059868Park JHChang YSong TJChung MKfalseAssociation of Oral Health with Risk of Rheumatoid Arthritis: A Nationwide Cohort Study.Periodontitis and rheumatoid arthritis (RA) are inflammatory diseases that share many similarities. We aimed to investigate the associations of periodontitis and oral hygiene status and behaviors with RA in a nationwide general population cohort. Participants from the National Health Screening cohort database of Korea who underwent oral health screening by dentists between 2003 and 2004 were included. The occurrence of RA was analyzed according to the presence of periodontitis, oral health examination findings, and behaviors. Overall, 2,239,586 participants were included. During a median of 16.7 years, RA occurred in 27,029 (1.2%) participants. The risk for incident RA was higher when participants had periodontitis (hazard ratio (HR) 1.2, 95% confidence interval (CI), 1.08-1.24) and an inc2023-01-01T00:00:00Z2023 Feb2025-08-24T03:08:24.866Z2025-04-04T08:53:00.947ZS-EPMC99604113683657410.3390/jpm13020340