{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dong Y"],"funding":["Jiangsu Agricultural Science and Technology Innovation Fund","China Agricultural Research System Program","Jiangsu key R & D plan (Modern Agriculture)"],"pagination":["3214"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9960685"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(4)"],"pubmed_abstract":["Fusarium head blight (FHB) is primarily caused by <i>Fusarium graminearum</i> and severely reduces wheat yield, causing mycotoxin contamination in grains and derived products. <i>F. graminearum</i>-secreted chemical toxins stably accumulate in plant cells, disturbing host metabolic homeostasis. We determined the potential mechanisms underlying FHB resistance and susceptibility in wheat. Three representative wheat varieties (Sumai 3, Yangmai 158, and Annong 8455) were inoculated with <i>F. graminearum</i> and their metabolite changes were assessed and compared. In total, 365 differentiated metabolites were successfully identified. Amino acids and derivatives, carbohydrates, flavonoids, hydroxycinnamate derivatives, lipids, and nucleotides constituted the major changes in response to fungal "],"journal":["International journal of molecular sciences"],"pubmed_title":["Investigating the Resistance Mechanism of Wheat Varieties to Fusarium Head Blight Using Comparative Metabolomics."],"pmcid":["PMC9960685"],"funding_grant_id":["CX(22)2133","CARS-03","(BE2022337; BE2021375)"],"pubmed_authors":["Yang X","Li G","Xia X","Wu L","Dong Y","He Y","Ahmad D","Zhang X","Wang Y","Jiang P","Zhang P"],"additional_accession":[]},"is_claimable":false,"name":"Investigating the Resistance Mechanism of Wheat Varieties to Fusarium Head Blight Using Comparative Metabolomics.","description":"Fusarium head blight (FHB) is primarily caused by <i>Fusarium graminearum</i> and severely reduces wheat yield, causing mycotoxin contamination in grains and derived products. <i>F. graminearum</i>-secreted chemical toxins stably accumulate in plant cells, disturbing host metabolic homeostasis. We determined the potential mechanisms underlying FHB resistance and susceptibility in wheat. Three representative wheat varieties (Sumai 3, Yangmai 158, and Annong 8455) were inoculated with <i>F. graminearum</i> and their metabolite changes were assessed and compared. In total, 365 differentiated metabolites were successfully identified. Amino acids and derivatives, carbohydrates, flavonoids, hydroxycinnamate derivatives, lipids, and nucleotides constituted the major changes in response to fungal ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-26T00:08:38.74Z","creation":"2025-04-06T09:32:23.483Z"},"accession":"S-EPMC9960685","cross_references":{"pubmed":["36834625"],"doi":["10.3390/ijms24043214"]}}