{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Mohamed AA"],"pubmed_abstract":["<h4>Background and aims</h4>SARS-CoV-2 infection has been recorded in 230 countries to date. Obesity has a negative impact on one's quality of life and is one of the main causes of mortality globally. Obesity affects the immune system, making the host more susceptible to infectious infections. Also, obesity commonly provokes the severity of respiratory diseases so the correlation of <i>LEP</i> rs7799039 Polymorphism in corpulent patients with COVID-19 infection was clearly investigated in the current study.<h4>Methods</h4>A total of 232 patients were recruited, 116 patients were obese with COVID-19 infection, and 116 patients were non obese COVID-19. Fasting blood glucose test (FBG), hemoglobin A1C (HbA1C), complete blood count (CBC), international normalized ratio (INR), urea, alanine tra"],"journal":["Diabetes, metabolic syndrome and obesity : targets and therapy"],"pagination":["515-522"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9961580"],"repository":["biostudies-literature"],"pubmed_title":["The Impact of <i>LEP</i> rs7799039 Polymorphism and Obesity on the Severity of Coronavirus Disease-19."],"pmcid":["PMC9961580"],"pubmed_authors":["Abdel Halim A","Abdel Salam S","Abdelghafour RAM","Mousa S","Alrohaimi AH","Alwaleed EA","Jafri I","Mohamed N","Adaroas AS","Elnagar RM","Abd El Salam SM","Eldeeb HH","Nassar NA","Mohamed AY","Mahmoud MO","El-Sayed M","Fayad E","Ramadan A","El-Kasses A","Mohamed AA","Sayed Abdelgeliel A","Albogami S","Mohammed MA"],"additional_accession":[]},"is_claimable":false,"name":"The Impact of <i>LEP</i> rs7799039 Polymorphism and Obesity on the Severity of Coronavirus Disease-19.","description":"<h4>Background and aims</h4>SARS-CoV-2 infection has been recorded in 230 countries to date. Obesity has a negative impact on one's quality of life and is one of the main causes of mortality globally. Obesity affects the immune system, making the host more susceptible to infectious infections. Also, obesity commonly provokes the severity of respiratory diseases so the correlation of <i>LEP</i> rs7799039 Polymorphism in corpulent patients with COVID-19 infection was clearly investigated in the current study.<h4>Methods</h4>A total of 232 patients were recruited, 116 patients were obese with COVID-19 infection, and 116 patients were non obese COVID-19. Fasting blood glucose test (FBG), hemoglobin A1C (HbA1C), complete blood count (CBC), international normalized ratio (INR), urea, alanine tra","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-05T16:39:15.066Z","creation":"2024-12-04T12:37:10.086Z"},"accession":"S-EPMC9961580","cross_references":{"pubmed":["36852180"],"doi":["10.2147/DMSO.S391869"]}}