{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huo C"],"funding":["NSFC","Cultivation Fund of the Key Scientific and Technical Innovation Project","Research Fund for the Doctoral Program of Higher Education and Ministry of Education of China"],"pagination":["136"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9961689"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(2)"],"pubmed_abstract":["Indene (IND) is a kind of important aromatic hydrocarbon that is extracted from coal tar and has important applications in industry and biology. In the process of production and utilization, it is easy to enter the soil and produce toxic effects on the soil or organisms. The earthworm is an important organism in the soil. The toxicity of indene on earthworm coelomocytes is rarely studied, and the oxidative stress effects of IND on earthworm coelomocytes remain unclear. In this study, coelomocytes from earthworms and antioxidant enzymes were selected as the research targets. In addition, IND caused oxidative stress, and its related toxic effects and mechanisms were systematically studied and evaluated at the cellular and molecular levels. The results showed that IND destroyed the redox bala"],"journal":["Toxics"],"pubmed_title":["Cytotoxicity and Oxidative Stress Effects of Indene on Coelomocytes of Earthworm (<i>Eisenia foetida</i>): Combined Analysis at Cellular and Molecular Levels."],"pmcid":["PMC9961689"],"funding_grant_id":["22276113","U1806216","21876103","708058","21777088"],"pubmed_authors":["Li X","He F","Jing M","Zhao Q","Zong W","Huo C","Wan J","Liu R"],"additional_accession":[]},"is_claimable":false,"name":"Cytotoxicity and Oxidative Stress Effects of Indene on Coelomocytes of Earthworm (<i>Eisenia foetida</i>): Combined Analysis at Cellular and Molecular Levels.","description":"Indene (IND) is a kind of important aromatic hydrocarbon that is extracted from coal tar and has important applications in industry and biology. In the process of production and utilization, it is easy to enter the soil and produce toxic effects on the soil or organisms. The earthworm is an important organism in the soil. The toxicity of indene on earthworm coelomocytes is rarely studied, and the oxidative stress effects of IND on earthworm coelomocytes remain unclear. In this study, coelomocytes from earthworms and antioxidant enzymes were selected as the research targets. In addition, IND caused oxidative stress, and its related toxic effects and mechanisms were systematically studied and evaluated at the cellular and molecular levels. The results showed that IND destroyed the redox bala","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-05-16T03:14:40.138Z","creation":"2025-02-18T23:44:41.297Z"},"accession":"S-EPMC9961689","cross_references":{"pubmed":["36851011"],"doi":["10.3390/toxics11020136"]}}