{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(4)"],"submitter":["Morel JB"],"pubmed_abstract":["<b>Purpose</b>: To follow the evolution of peripheral ischemia by fluorescein angiography (FA) on ultra-wide-field (UWF) images in diabetic patients treated with anti-vascular endothelial growth factor (anti-VEGF) for macular edema. <b>Methods</b>: Prospective, non-interventional cohort study analyzing UWF-FA images of 48 patients with diabetic retinopathy (48 eyes) treated for diabetic macular edema. UWF-FA was performed at baseline and after one year of anti-VEGF therapy (M12). The primary endpoint was the change in the non-perfusion index. <b>Results</b>: Of the 48 patients included in this study, 25 completed the one-year follow-up, and 20 had FA images of sufficient quality to be interpreted. The non-perfusion index did not significantly change from baseline after one year of anti-VEG"],"journal":["Journal of clinical medicine"],"pagination":["1365"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9963628"],"repository":["biostudies-literature"],"pubmed_title":["Ultra-Wide-Field Fluorescein Angiography Assessment of Non-Perfusion in Patients with Diabetic Retinopathy Treated with Anti-Vascular Endothelial Growth Factor Therapy."],"pmcid":["PMC9963628"],"pubmed_authors":["Giocanti-Auregan A","Amari F","Morel JB","Fajnkuchen F","Bloch-Queyrat C","Sritharan N"],"additional_accession":[]},"is_claimable":false,"name":"Ultra-Wide-Field Fluorescein Angiography Assessment of Non-Perfusion in Patients with Diabetic Retinopathy Treated with Anti-Vascular Endothelial Growth Factor Therapy.","description":"<b>Purpose</b>: To follow the evolution of peripheral ischemia by fluorescein angiography (FA) on ultra-wide-field (UWF) images in diabetic patients treated with anti-vascular endothelial growth factor (anti-VEGF) for macular edema. <b>Methods</b>: Prospective, non-interventional cohort study analyzing UWF-FA images of 48 patients with diabetic retinopathy (48 eyes) treated for diabetic macular edema. UWF-FA was performed at baseline and after one year of anti-VEGF therapy (M12). The primary endpoint was the change in the non-perfusion index. <b>Results</b>: Of the 48 patients included in this study, 25 completed the one-year follow-up, and 20 had FA images of sufficient quality to be interpreted. The non-perfusion index did not significantly change from baseline after one year of anti-VEG","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-04T21:44:20.619Z","creation":"2025-04-04T21:44:20.619Z"},"accession":"S-EPMC9963628","cross_references":{"pubmed":["36835902"],"doi":["10.3390/jcm12041365"]}}