{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cavka L"],"funding":["Slovenian Research Agency","lovenian Research Agency (ARRS)"],"pagination":["1044"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9964768"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(4)"],"pubmed_abstract":["<h4>Purpose</h4>Prognostic role of nutritional status (NS) in patients with metastatic castrate-resistant prostate cancer (mCRPC) is unknown. We hypothesized that patients' NS at the presentation of mCRPC is prognostic for health-related quality of life (HRQoL) and overall survival (OS).<h4>Methods</h4>We conducted a prospective observational study in mCRPC patients. At enrollment, we allocated each patient into one of four NS categories: (i) well-nourished (WN), (ii) nutritional risk without sarcopenia/cachexia (NR), (iii) sarcopenia, or (iv) cachexia. We sought the prognostic role of the NS for OS and HRQoL by regression models.<h4>Results</h4>141 patients were included into our study. When compared to WN patients, those with NR and cachexia had a higher chance of worse HRQoL (OR 3.45; 9"],"journal":["Nutrients"],"pubmed_title":["Prognostic Impact of Nutritional Status on Overall Survival and Health-Related Quality of Life in Men with Advanced Prostate Cancer."],"pmcid":["PMC9964768"],"funding_grant_id":["P3-0321"],"pubmed_authors":["Rotovnik Kozjek N","Seruga B","Cavka L","Pohar Perme M"],"additional_accession":[]},"is_claimable":false,"name":"Prognostic Impact of Nutritional Status on Overall Survival and Health-Related Quality of Life in Men with Advanced Prostate Cancer.","description":"<h4>Purpose</h4>Prognostic role of nutritional status (NS) in patients with metastatic castrate-resistant prostate cancer (mCRPC) is unknown. We hypothesized that patients' NS at the presentation of mCRPC is prognostic for health-related quality of life (HRQoL) and overall survival (OS).<h4>Methods</h4>We conducted a prospective observational study in mCRPC patients. At enrollment, we allocated each patient into one of four NS categories: (i) well-nourished (WN), (ii) nutritional risk without sarcopenia/cachexia (NR), (iii) sarcopenia, or (iv) cachexia. We sought the prognostic role of the NS for OS and HRQoL by regression models.<h4>Results</h4>141 patients were included into our study. When compared to WN patients, those with NR and cachexia had a higher chance of worse HRQoL (OR 3.45; 9","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-08-24T03:08:26.1Z","creation":"2025-04-04T08:53:13.15Z"},"accession":"S-EPMC9964768","cross_references":{"pubmed":["36839402"],"doi":["10.3390/nu15041044"]}}