{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Silhavy J"],"funding":["Czech Science Foundation project","National Institute for Research of Metabolic and Cardiovascular Diseases","Ministry of Education Youth and Sports, RVO","RVO","European Union—Next Generation EU","National Institute for Research of Metabolic and Cardiovascular Diseases (Program EXCELES, ID Project No. LX22NPO5104) funded by the European Union - Next Generation EU"],"pagination":["192"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9965406"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(2)"],"pubmed_abstract":["Recently, red beetroot has attracted attention as a health-promoting functional food. Studies have shown that beetroot administration can reduce blood pressure and ameliorate parameters of glucose and lipid metabolism; however, mechanisms underlying these beneficial effects of beetroot are not yet fully understood. In the current study, we analysed the effects of beetroot on parameters of glucose and lipid metabolism in two models of metabolic syndrome: (i) transgenic spontaneously hypertensive rats expressing human C-reactive protein (SHR-CRP rats), and (ii) hereditary hypertriglyceridemic (HHTg) rats. Treatment with beetroot juice for 4 weeks was, in both models, associated with amelioration of oxidative stress, reduced circulating lipids, smaller visceral fat depots, and lower ectopic f"],"journal":["Metabolites"],"pubmed_title":["Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome."],"pmcid":["PMC9965406"],"funding_grant_id":["21-18993S","LX22NPO5104","67985823","68378050"],"pubmed_authors":["Simakova M","Markova I","Vrbacky M","Pecinova A","Mlejnek P","Kazdova L","Mracek T","Malinska H","Miklankova D","Huttl M","Silhavy J","Pravenec M"],"additional_accession":[]},"is_claimable":false,"name":"Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome.","description":"Recently, red beetroot has attracted attention as a health-promoting functional food. Studies have shown that beetroot administration can reduce blood pressure and ameliorate parameters of glucose and lipid metabolism; however, mechanisms underlying these beneficial effects of beetroot are not yet fully understood. In the current study, we analysed the effects of beetroot on parameters of glucose and lipid metabolism in two models of metabolic syndrome: (i) transgenic spontaneously hypertensive rats expressing human C-reactive protein (SHR-CRP rats), and (ii) hereditary hypertriglyceridemic (HHTg) rats. Treatment with beetroot juice for 4 weeks was, in both models, associated with amelioration of oxidative stress, reduced circulating lipids, smaller visceral fat depots, and lower ectopic f","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-04-08T12:45:46.962Z","creation":"2025-02-18T23:57:38.439Z"},"accession":"S-EPMC9965406","cross_references":{"pubmed":["36837811"],"doi":["10.3390/metabo13020192"]}}