biostudies-literatureUnknown12(4)Williams LD<h4>Introduction</h4>SARS-CoV-2, responsible for the coronavirus disease (COVID-19) pandemic, may impact other systems apart from the respiratory system, including the nervous system. In this systematic review, we aimed to establish the prevalence and determinants of neuropathic pain amongst COVID-19-infected individuals.<h4>Methodology</h4>A literature search in the PubMed database was performed and 11 papers were eligible for inclusion in this systematic review and meta-analysis.<h4>Results</h4>The pooled prevalence of COVID-19-related neuropathic pain was 6.7% (95% CI: 4.7-9.5%) for hospitalised patients during the acute phase and 34.3% (95% CI: 14.3-62%) for long COVID patients. The identified risk factors for COVID-19-related neuropathic pain development included depression, COVID-19 severity and azithromycin use.<h4>Conclusions</h4>Neuropathic pain is a very common symptom in long COVID, indicating the urgency for further research in this direction.Journal of clinical medicine1672https://www.ebi.ac.uk/biostudies/studies/S-EPMC9966617biostudies-literatureCOVID-19-Related Neuropathic Pain: A Systematic Review and Meta-Analysis.PMC9966617Zis PWilliams LDfalseCOVID-19-Related Neuropathic Pain: A Systematic Review and Meta-Analysis.<h4>Introduction</h4>SARS-CoV-2, responsible for the coronavirus disease (COVID-19) pandemic, may impact other systems apart from the respiratory system, including the nervous system. In this systematic review, we aimed to establish the prevalence and determinants of neuropathic pain amongst COVID-19-infected individuals.<h4>Methodology</h4>A literature search in the PubMed database was performed and 11 papers were eligible for inclusion in this systematic review and meta-analysis.<h4>Results</h4>The pooled prevalence of COVID-19-related neuropathic pain was 6.7% (95% CI: 4.7-9.5%) for hospitalised patients during the acute phase and 34.3% (95% CI: 14.3-62%) for long COVID patients. The identified risk factors for COVID-19-related neuropathic pain development included depression, COVID-19 severity and azithromycin use.<h4>Conclusions</h4>Neuropathic pain is a very common symptom in long COVID, indicating the urgency for further research in this direction.2023-01-01T00:00:00Z2023 Feb2025-04-26T00:05:12.643Z2025-02-18T23:58:04.963ZS-EPMC99666173683620710.3390/jcm12041672