biostudies-literatureLevin JCU.S. National Library of MedicineNHLBI NIH HHSNational Heart, Lung, and Blood InstituteNLM NIH HHSe133-e141https://www.ebi.ac.uk/biostudies/studies/S-EPMC9969323biostudies-literatureUnknown41(S 01)<h4>Objectives</h4>Our objective was to compare rates of hospitalizations for respiratory illnesses in preterm and full-term (FT) children for 4 years before and after the 2014 update to the American Academy of Pediatrics (AAP) respiratory syncytial virus (RSV) immunoprophylaxis guidance, which restricted eligibility among infants born at 29 to 34 weeks in the first winter and all preterm infants in the second winter after neonatal discharge.<h4>Study design</h4>We conducted pre-post and interrupted time series analyses on claims data from a commercial national managed care plan. We compared the number of RSV and all respiratory hospital admissions in the first and second RSV seasons after neonatal discharge among a cohort of preterm children, regardless of palivizumab status, in the 4 yeaAmerican journal of perinatologyCost Savings Without Increased Risk of Respiratory Hospitalization for Preterm Children after the 2014 Palivizumab Policy Update.PMC9969323K23 HL136851K01 HL141771T15 LM007092T15LM007092Fox KPBeam ALLevin JCHayden LPfalseCost Savings Without Increased Risk of Respiratory Hospitalization for Preterm Children after the 2014 Palivizumab Policy Update.<h4>Objectives</h4>Our objective was to compare rates of hospitalizations for respiratory illnesses in preterm and full-term (FT) children for 4 years before and after the 2014 update to the American Academy of Pediatrics (AAP) respiratory syncytial virus (RSV) immunoprophylaxis guidance, which restricted eligibility among infants born at 29 to 34 weeks in the first winter and all preterm infants in the second winter after neonatal discharge.<h4>Study design</h4>We conducted pre-post and interrupted time series analyses on claims data from a commercial national managed care plan. We compared the number of RSV and all respiratory hospital admissions in the first and second RSV seasons after neonatal discharge among a cohort of preterm children, regardless of palivizumab status, in the 4 yea2024-01-01T00:00:00Z2024 May2025-07-08T03:11:35.699Z2025-07-08T03:11:35.699ZS-EPMC99693233552341010.1055/a-1845-2184