{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jin D"],"funding":["National Natural Science Foundation of China"],"pagination":["83"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9969648"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Objectives</h4>This study aimed to assess the epidemiological features and explore the potential risk factors for early neurological deterioration (END) in patients with acute single small subcortical infarction (SSSI) who underwent antiplatelet therapy without carotid artery stenosis.<h4>Materials & methods</h4>Patients with SSSI, as confirmed by cranial magnetic resonance imaging (MRI), who were hospitalized within 48 h after the onset of symptoms were enrolled. END was mainly defined as increment in the National Institutes of Health Stroke Scale (NIHSS) score of ≥ 2 points or any new neurological deficit. Poor functional outcome was defined as modified Rankin Scale (mRS) score of > 2 points at 3-month after the onset. The association of END with multiple indicators was assessed at t"],"journal":["BMC neurology"],"pubmed_title":["Risk factors for early neurologic deterioration in single small subcortical infarction without carrier artery stenosis: predictors at the early stage."],"pmcid":["PMC9969648"],"funding_grant_id":["6197011271"],"pubmed_authors":["Liu H","Yang J","Dong Y","Zhu H","Zhang L","Luo B","Shan Y","Wang P","Wang Q","Jin D","Zhang X","Du J","Wu Y"],"additional_accession":[]},"is_claimable":false,"name":"Risk factors for early neurologic deterioration in single small subcortical infarction without carrier artery stenosis: predictors at the early stage.","description":"<h4>Objectives</h4>This study aimed to assess the epidemiological features and explore the potential risk factors for early neurological deterioration (END) in patients with acute single small subcortical infarction (SSSI) who underwent antiplatelet therapy without carotid artery stenosis.<h4>Materials & methods</h4>Patients with SSSI, as confirmed by cranial magnetic resonance imaging (MRI), who were hospitalized within 48 h after the onset of symptoms were enrolled. END was mainly defined as increment in the National Institutes of Health Stroke Scale (NIHSS) score of ≥ 2 points or any new neurological deficit. Poor functional outcome was defined as modified Rankin Scale (mRS) score of > 2 points at 3-month after the onset. The association of END with multiple indicators was assessed at t","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-05-29T19:43:32.553Z","creation":"2025-04-04T21:47:54.546Z"},"accession":"S-EPMC9969648","cross_references":{"pubmed":["36849878"],"doi":["10.1186/s12883-023-03128-3"]}}