{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Schellenberg M"],"funding":["NHLBI NIH HHS"],"pagination":["484-489"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9970012"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["94(3)"],"pubmed_abstract":["<h4>Abstract</h4>Optimizing prophylaxis against venous thromboembolic events (VTEs) is a critical issue in the care of injured patients. Although these patients are at significant risk of developing VTE, they also present competing concerns related to exacerbation of bleeding from existing injuries. Especially after high-risk trauma, including injuries to the abdominal solid organs, brain, and spine, trauma providers must delineate the time period in which VTE prophylaxis successfully reduces VTE rates without encouraging bleeding. Although existing data are primarily retrospective in nature and further study is required, literature supports early VTE chemoprophylaxis initiation even for severely injured patients. Early initiation is most frequently defined as <48 hours from admission but "],"journal":["The journal of trauma and acute care surgery"],"pubmed_title":["Timing of venous thromboembolism prophylaxis initiation after injury: Findings from the consensus conference to implement optimal VTE prophylaxis in trauma."],"pmcid":["PMC9970012"],"funding_grant_id":["R13 HL158206"],"pubmed_authors":["Bernard AC","Price MA","Haut ER","Costantini T","Joseph B","Schellenberg M"],"additional_accession":[]},"is_claimable":false,"name":"Timing of venous thromboembolism prophylaxis initiation after injury: Findings from the consensus conference to implement optimal VTE prophylaxis in trauma.","description":"<h4>Abstract</h4>Optimizing prophylaxis against venous thromboembolic events (VTEs) is a critical issue in the care of injured patients. Although these patients are at significant risk of developing VTE, they also present competing concerns related to exacerbation of bleeding from existing injuries. Especially after high-risk trauma, including injuries to the abdominal solid organs, brain, and spine, trauma providers must delineate the time period in which VTE prophylaxis successfully reduces VTE rates without encouraging bleeding. Although existing data are primarily retrospective in nature and further study is required, literature supports early VTE chemoprophylaxis initiation even for severely injured patients. Early initiation is most frequently defined as <48 hours from admission but ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-03T23:50:15.894Z","creation":"2025-04-03T23:50:15.894Z"},"accession":"S-EPMC9970012","cross_references":{"pubmed":["36729602"],"doi":["10.1097/TA.0000000000003847","10.1097/ta.0000000000003847"]}}