biostudies-literatureUnknown12Ko J<h4>Background</h4>Excessive dietary sodium intake is an independent risk factor for hypertension and cardiovascular disease (CVD). Despite the large body of evidence concerning the effects of dietary interventions on blood pressure (BP) and CVD outcomes, trials have often reported low adherence to decreased sodium intake, likely due in part to heterogeneous BP responses. To address the challenges, recent clinical findings suggested a precise and personalized dietary approach that seeks to deliver more preventive and practical dietary advice than the "one-size-fits-all" guidelines and weighs the personal risk of developing specific diseases.<h4>Objective</h4>The purpose of this pilot randomized controlled trial was to test the feasibility and preliminary efficacy of integrating the use of JMIR research protocolse39058https://www.ebi.ac.uk/biostudies/studies/S-EPMC9972206biostudies-literatureExamining the Individual Response to a Low-Sodium Diet in Patients with Hypertension: Protocol for a Pilot Randomized Controlled Trial.PMC9972206Sharma KKo JWang JChung MLfalseExamining the Individual Response to a Low-Sodium Diet in Patients with Hypertension: Protocol for a Pilot Randomized Controlled Trial.<h4>Background</h4>Excessive dietary sodium intake is an independent risk factor for hypertension and cardiovascular disease (CVD). Despite the large body of evidence concerning the effects of dietary interventions on blood pressure (BP) and CVD outcomes, trials have often reported low adherence to decreased sodium intake, likely due in part to heterogeneous BP responses. To address the challenges, recent clinical findings suggested a precise and personalized dietary approach that seeks to deliver more preventive and practical dietary advice than the "one-size-fits-all" guidelines and weighs the personal risk of developing specific diseases.<h4>Objective</h4>The purpose of this pilot randomized controlled trial was to test the feasibility and preliminary efficacy of integrating the use of 2023-01-01T00:00:00Z2023 Feb2025-04-19T02:46:26.086Z2025-04-07T13:05:41.794ZS-EPMC99722063678021010.2196/39058