{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(3)"],"submitter":["Chen X"],"pubmed_abstract":["Candida haemulonii, a relative of C. auris, frequently shows antifungal resistance and is transmissible. However, molecular tools for genotyping and investigating outbreaks are not yet established. We performed genome-based population analysis on 94 C. haemulonii strains, including 58 isolates from China and 36 other published strains. Phylogenetic analysis revealed that C. haemulonii can be divided into 4 clades. Clade 1 comprised strains from China and other global strains; clades 2-4 contained only isolates from China, were more recently evolved, and showed higher antifungal resistance. Four regional epidemic clusters (A, B, C, and D) were identified in China, each comprising ≥5 cases (largest intracluster pairwise single-nucleotide polymorphism differences <50 bp). Cluster A was identi"],"journal":["Emerging infectious diseases"],"pagination":["576-584"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9973686"],"repository":["biostudies-literature"],"pubmed_title":["Clonal Dissemination of Antifungal-Resistant Candida haemulonii, China."],"pmcid":["PMC9973686"],"pubmed_authors":["Zhang G","Huang J","Zhang J","Zhang H","Lin Y","Wang H","Hou X","Zhang Q","Xi H","Bing J","Liu Y","Liu Z","Jia X","Kang M","Wang W","Chen X","Gong J","Hong N","Fan X","Kang W","Xie X","Xiao Y","Yang B","Xu H","Li L","Xu J","Yang W","Xiao M","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Clonal Dissemination of Antifungal-Resistant Candida haemulonii, China.","description":"Candida haemulonii, a relative of C. auris, frequently shows antifungal resistance and is transmissible. However, molecular tools for genotyping and investigating outbreaks are not yet established. We performed genome-based population analysis on 94 C. haemulonii strains, including 58 isolates from China and 36 other published strains. Phylogenetic analysis revealed that C. haemulonii can be divided into 4 clades. Clade 1 comprised strains from China and other global strains; clades 2-4 contained only isolates from China, were more recently evolved, and showed higher antifungal resistance. Four regional epidemic clusters (A, B, C, and D) were identified in China, each comprising ≥5 cases (largest intracluster pairwise single-nucleotide polymorphism differences <50 bp). Cluster A was identi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2026-05-28T12:52:18.829Z","creation":"2025-04-05T22:50:56.226Z"},"accession":"S-EPMC9973686","cross_references":{"pubmed":["36823029"],"doi":["10.3201/eid2903.221082"]}}