{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yetmar ZA"],"funding":["NCATS NIH HHS"],"pagination":["782-791"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9974559"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["107(3)"],"pubmed_abstract":["<h4>Background</h4>Nocardia is an environmental pathogen with a predilection for causing opportunistic infections in immunocompromised patients, including solid organ transplant (SOT) recipients. Although risk factors have been identified for developing nocardiosis in this population, little is known regarding clinical factors resulting in poor outcomes. We evaluated a cohort of SOT recipients with nocardiosis for associations with 12-month mortality.<h4>Methods</h4>We performed a multicenter retrospective cohort study of adult SOT recipients diagnosed with culture-confirmed nocardiosis from 2000 to 2020. Patients were followed for 12 months after diagnosis, unless abbreviated by mortality. Multivariable Cox regression was performed to analyze associations with 12-month mortality. A subgro"],"journal":["Transplantation"],"pubmed_title":["Outcomes of Nocardiosis and Treatment of Disseminated Infection in Solid Organ Transplant Recipients."],"pmcid":["PMC9974559"],"funding_grant_id":["UL1 TR002377"],"pubmed_authors":["Seville MT","Challener DW","Beam E","Bosch W","Yetmar ZA"],"additional_accession":[]},"is_claimable":false,"name":"Outcomes of Nocardiosis and Treatment of Disseminated Infection in Solid Organ Transplant Recipients.","description":"<h4>Background</h4>Nocardia is an environmental pathogen with a predilection for causing opportunistic infections in immunocompromised patients, including solid organ transplant (SOT) recipients. Although risk factors have been identified for developing nocardiosis in this population, little is known regarding clinical factors resulting in poor outcomes. We evaluated a cohort of SOT recipients with nocardiosis for associations with 12-month mortality.<h4>Methods</h4>We performed a multicenter retrospective cohort study of adult SOT recipients diagnosed with culture-confirmed nocardiosis from 2000 to 2020. Patients were followed for 12 months after diagnosis, unless abbreviated by mortality. Multivariable Cox regression was performed to analyze associations with 12-month mortality. A subgro","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-03T23:50:19.481Z","creation":"2025-04-03T23:50:19.481Z"},"accession":"S-EPMC9974559","cross_references":{"pubmed":["36303280"],"doi":["10.1097/tp.0000000000004343","10.1097/TP.0000000000004343"]}}