biostudies-literatureUnknown14Song YNational Natural Science Foundation of ChinaNational Key Research and Development Program of China<h4>Background</h4>Remnant cholesterol (RC) has been correlated with a higher risk of atherosclerosis. It has been confirmed that in the general population, an elevated RC level is related to a 5-fold higher risk of peripheral arterial disease (PAD). Diabetes is one of the strongest risk factors for PAD development. However, the association between RC and PAD in the specific population of type 2 diabetes mellitus (T2DM) has not been investigated. Herein, the correlation was investigated between RC and PAD in T2DM patients.<h4>Methods</h4>In the retrospective study, the hematological parameter data of 246 T2DM patients without PAD (T2DM - WPAD) and 270 T2DM patients with PAD (T2DM - PAD) was collected. Differences in RC levels between the two groups were compared, and the association betweeFrontiers in endocrinology1111152https://www.ebi.ac.uk/biostudies/studies/S-EPMC9974817biostudies-literatureRemnant cholesterol is independently asssociated with an increased risk of peripheral artery disease in type 2 diabetic patients.PMC9974817Jin SShu YZhang LCheng WBai XZhao YSong YWang LShu MfalseRemnant cholesterol is independently asssociated with an increased risk of peripheral artery disease in type 2 diabetic patients.<h4>Background</h4>Remnant cholesterol (RC) has been correlated with a higher risk of atherosclerosis. It has been confirmed that in the general population, an elevated RC level is related to a 5-fold higher risk of peripheral arterial disease (PAD). Diabetes is one of the strongest risk factors for PAD development. However, the association between RC and PAD in the specific population of type 2 diabetes mellitus (T2DM) has not been investigated. Herein, the correlation was investigated between RC and PAD in T2DM patients.<h4>Methods</h4>In the retrospective study, the hematological parameter data of 246 T2DM patients without PAD (T2DM - WPAD) and 270 T2DM patients with PAD (T2DM - PAD) was collected. Differences in RC levels between the two groups were compared, and the association betwee2023-01-01T00:00:00Z20232025-05-31T23:51:24.025Z2024-11-12T12:56:23.798ZS-EPMC99748173687545210.3389/fendo.2023.1111152