biostudies-literatureUnknown58Garnier M<h4>Background</h4>Preoperative COVID-19 has been associated with excess postoperative morbi-mortality. Consequently, guidelines were developed that recommended the postponement of surgery for at least 7 weeks after the infection. We hypothesised that vaccination against the SARS-CoV-2 and the large predominance of the Omicron variant attenuated the effect of a preoperative COVID-19 on the occurrence of postoperative respiratory morbidity.<h4>Methods</h4>We conducted a prospective cohort study in 41 French centres between 15 March and 30 May 2022 (ClinicalTrials NCT05336110), aimed at comparing the postoperative respiratory morbidity between patients with and without preoperative COVID-19 within 8 weeks prior to surgery. The primary outcome was a composite outcome combining the occurrence EClinicalMedicine101881https://www.ebi.ac.uk/biostudies/studies/S-EPMC9975647biostudies-literatureAssociation of preoperative COVID-19 and postoperative respiratory morbidity during the Omicron epidemic wave: the DROMIS-22 multicentre prospective observational cohort study.PMC9975647Frasca DMazeraud ABleuze PDo-Khac MLeger MGouel ASalettes RJozefowicz ERenard JMonziols SConstantin JMLeone MBardon JPenven PSigaut SRoland EQuesnel CBlanie ADaoui CZbidi BGarrigue DDegryse CRaft JPichon XCinotti RLopez SBonnet MPBezulier KLagarde KCaillard APiat CMrozek SPlouviez QRochon CEFki MBucciero MDegos VAries PLapidus NImauven OChipouline YRoy CPottecher JPelen FDaoud LNoll EDROMIS-22 Study Group and the SFAR Research NetworkDuchesne MDelerue CSimeone PAbrard SRangeard OParies MAndrianjatovo HMayeur NDeryckere STrehel-Tursis VThiriet CBrocas EHafiani EMLaurent QPuel FDiemunsch SBouchereau EDupont JEdouard DDe Courson HVelly LBiais MDeransy RFavreau MBidon CRineau EDestruhaut GDanguy des Deserts MHuet OCambriel ACheron-Leroy DVerdonk FRobin JJSoldan LVoulgaropoulos JChaouche SThion LAOttolenghi LDufour GCharbonneau HFigueiredo SPastene BEspitalier FGayat EMercier FQuemeneur CBoolad MPollet AGarnier MJoannes-Boyau OSchmitt JLecinq AMargetis DCirenei CLasocki SPlaud BDescamps RLigneres LfalseAssociation of preoperative COVID-19 and postoperative respiratory morbidity during the Omicron epidemic wave: the DROMIS-22 multicentre prospective observational cohort study.<h4>Background</h4>Preoperative COVID-19 has been associated with excess postoperative morbi-mortality. Consequently, guidelines were developed that recommended the postponement of surgery for at least 7 weeks after the infection. We hypothesised that vaccination against the SARS-CoV-2 and the large predominance of the Omicron variant attenuated the effect of a preoperative COVID-19 on the occurrence of postoperative respiratory morbidity.<h4>Methods</h4>We conducted a prospective cohort study in 41 French centres between 15 March and 30 May 2022 (ClinicalTrials NCT05336110), aimed at comparing the postoperative respiratory morbidity between patients with and without preoperative COVID-19 within 8 weeks prior to surgery. The primary outcome was a composite outcome combining the occurrence 2023-01-01T00:00:00Z2023 Apr2026-07-14T20:18:31.945Z2024-12-04T12:39:06.222ZS-EPMC99756473687342510.1016/j.eclinm.2023.101881