{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(2)"],"submitter":["Pettee Gabriel K"],"pubmed_abstract":["<h4>Importance</h4>Optimizing cardiovascular fitness is a prevention strategy against premature death and cardiovascular disease (CVD) events. Since this evidence has largely been established in older populations, the importance of cardiorespiratory fitness during earlier periods of adulthood remains unclear.<h4>Objective</h4>To examine the association of early-adulthood cardiorespiratory fitness and percentage of early-adulthood cardiorespiratory fitness retained during midlife with subsequent risk of all-cause mortality and CVD-related morbidity and mortality overall as well as by sex and race.<h4>Design, setting, and participants</h4>This retrospective population-based cohort study analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, an ongoing prospec"],"journal":["JAMA network open"],"pagination":["e230842"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9975906"],"repository":["biostudies-literature"],"pubmed_title":["Analysis of Cardiorespiratory Fitness in Early Adulthood and Midlife With All-Cause Mortality and Fatal or Nonfatal Cardiovascular Disease."],"pmcid":["PMC9975906"],"pubmed_authors":["Lewis CE","Hornikel B","Sternfeld B","Schreiner PJ","Jaeger BC","Shikany JM","Whitaker KM","Dooley EE","Pettee Gabriel K","Sidney S","Carnethon MR","Jacobs DR","Reis JP","Arynchyn A"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of Cardiorespiratory Fitness in Early Adulthood and Midlife With All-Cause Mortality and Fatal or Nonfatal Cardiovascular Disease.","description":"<h4>Importance</h4>Optimizing cardiovascular fitness is a prevention strategy against premature death and cardiovascular disease (CVD) events. Since this evidence has largely been established in older populations, the importance of cardiorespiratory fitness during earlier periods of adulthood remains unclear.<h4>Objective</h4>To examine the association of early-adulthood cardiorespiratory fitness and percentage of early-adulthood cardiorespiratory fitness retained during midlife with subsequent risk of all-cause mortality and CVD-related morbidity and mortality overall as well as by sex and race.<h4>Design, setting, and participants</h4>This retrospective population-based cohort study analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, an ongoing prospec","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-05T14:19:56.407Z","creation":"2025-04-05T14:19:56.407Z"},"accession":"S-EPMC9975906","cross_references":{"pubmed":["36853610"],"doi":["10.1001/jamanetworkopen.2023.0842"]}}