{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Waschke L"],"funding":["NINDS NIH HHS"],"pubmed_abstract":["During memory formation, the hippocampus is presumed to represent the content of stimuli, but how it does so is unknown. Using computational modelling and human single-neuron recordings, we show that the more precisely hippocampal spiking variability tracks the composite features of each individual stimulus, the better those stimuli are later remembered. We propose that moment-to-moment spiking variability may provide a new window into how the hippocampus constructs memories from the building blocks of our sensory world."],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2023.02.23.529684"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9980052"],"repository":["biostudies-literature"],"pubmed_title":["Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans."],"pmcid":["PMC9980052"],"funding_grant_id":["U01 NS117839"],"pubmed_authors":["Krishna S","Kamp F","van den Elzen E","Lindenberger U","Rutishauser U","Waschke L","Garrett DD"],"additional_accession":[]},"is_claimable":false,"name":"Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans.","description":"During memory formation, the hippocampus is presumed to represent the content of stimuli, but how it does so is unknown. Using computational modelling and human single-neuron recordings, we show that the more precisely hippocampal spiking variability tracks the composite features of each individual stimulus, the better those stimuli are later remembered. We propose that moment-to-moment spiking variability may provide a new window into how the hippocampus constructs memories from the building blocks of our sensory world.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Feb","modification":"2025-08-15T03:07:33.275Z","creation":"2025-04-04T19:17:59.64Z"},"accession":"S-EPMC9980052","cross_references":{"pubmed":["36865320"],"doi":["10.1101/2023.02.23.529684"]}}