biostudies-literatureUnknown10Liu X<h4>Background</h4>Sarcopenia leads to complications (infections, hepatic encephalopathy and ascites) and poor overall survival in patients with cirrhosis, in which the phenotypic presentation is loss of muscle mass. This study aimed to reveal the metabolic profile and identify potential biomarkers in cirrhotic patients with hepatitis B virus and muscle mass loss.<h4>Method</h4>Twenty decompensated cirrhotic patients with HBV and muscle mass loss were designated Group S; 20 decompensated cirrhotic patients with HBV and normal muscle mass were designated Group NS; and 20 healthy people were designated Group H. Muscle mass loss was defined as the skeletal muscle mass index less than 46.96 cm²/m² for males and less than 32.46 cm²/m² for females. GasFrontiers in nutrition1068779https://www.ebi.ac.uk/biostudies/studies/S-EPMC9980345biostudies-literatureDifferential metabolites in cirrhotic patients with hepatitis B and muscle mass loss.PMC9980345Liu XJiang YJing XDing XGuan GHan LBi SNiu QSheng QfalseDifferential metabolites in cirrhotic patients with hepatitis B and muscle mass loss.<h4>Background</h4>Sarcopenia leads to complications (infections, hepatic encephalopathy and ascites) and poor overall survival in patients with cirrhosis, in which the phenotypic presentation is loss of muscle mass. This study aimed to reveal the metabolic profile and identify potential biomarkers in cirrhotic patients with hepatitis B virus and muscle mass loss.<h4>Method</h4>Twenty decompensated cirrhotic patients with HBV and muscle mass loss were designated Group S; 20 decompensated cirrhotic patients with HBV and normal muscle mass were designated Group NS; and 20 healthy people were designated Group H. Muscle mass loss was defined as the skeletal muscle mass index less than 46.96 cm²/m² for males and less than 32.46 cm²/m² for females. Gas2023-01-01T00:00:00Z20232026-05-29T01:18:19.837Z2024-11-06T20:23:41.471ZS-EPMC99803453687583610.3389/fnut.2023.1068779