biostudies-literatureUnknown3(1)Ren QW<h4>Background</h4>Heart failure (HF) may increase the risk of dementia via shared risk factors.<h4>Objectives</h4>The authors investigated the incidence, types, clinical correlates, and prognostic impact of dementia in a population-based cohort of patients with index HF.<h4>Methods</h4>The previously territory-wide database was interrogated to identify eligible patients with HF (N = 202,121) from 1995 to 2018. Clinical correlates of incident dementia and their associations with all-cause mortality were assessed using multivariable Cox/competing risk regression models where appropriate.<h4>Results</h4>Among a total cohort aged ≥18 years with HF (mean age 75.3 ± 13.0 years, 51.3% women, median follow-up 4.1 [IQR: 1.2-10.2] years), new-onset dementia occurred in 22,145 (11.0%), with age-stanJACC. Asia108-119https://www.ebi.ac.uk/biostudies/studies/S-EPMC9982209biostudies-literatureIncidence, Clinical Correlates, and Prognostic Impact of Dementia in Heart Failure: A Population-Based Cohort Study.PMC9982209Tse HFOuwerkerk WRen QWYiu KHTeramoto KLi XLHung DChen CYuk Yuen JKWu MZYu SYKatherine Teng THHuang JYTay WTTse YKLam CSPLi HLChandramouli CTromp JfalseIncidence, Clinical Correlates, and Prognostic Impact of Dementia in Heart Failure: A Population-Based Cohort Study.<h4>Background</h4>Heart failure (HF) may increase the risk of dementia via shared risk factors.<h4>Objectives</h4>The authors investigated the incidence, types, clinical correlates, and prognostic impact of dementia in a population-based cohort of patients with index HF.<h4>Methods</h4>The previously territory-wide database was interrogated to identify eligible patients with HF (N = 202,121) from 1995 to 2018. Clinical correlates of incident dementia and their associations with all-cause mortality were assessed using multivariable Cox/competing risk regression models where appropriate.<h4>Results</h4>Among a total cohort aged ≥18 years with HF (mean age 75.3 ± 13.0 years, 51.3% women, median follow-up 4.1 [IQR: 1.2-10.2] years), new-onset dementia occurred in 22,145 (11.0%), with age-stan2023-01-01T00:00:00Z2023 Feb2025-05-29T16:30:25.784Z2025-05-29T16:30:25.784ZS-EPMC99822093687376810.1016/j.jacasi.2022.09.016