{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Ndlovu IS"],"funding":["Neurosurgical Research Foundation"],"pubmed_abstract":["<i>Trichinella</i> infections have been documented globally and have been detected in wild and/or domestic animals except Antarctica. There is paucity of information in the metabolic responses of hosts during <i>Trichinella</i> infections and biomarkers for infection that can be used in the diagnosis of the disease. The current study aimed to apply a non-targeted metabolomic approach to identify <i>Trichinella zimbabwensis</i> biomarkers including metabolic response from sera of infected Sprague-Dawley rats. Fifty-four male Sprague-Dawley rats were randomly assigned into <i>T. zimbabwensis</i> infected group (<i>n</i> = 36) and the non-infected control (<i>n</i> = 18). Results from the study showed that the metabolic signature of <i>T. zimbabwensis</i> infection consists of enriched methyl"],"journal":["Frontiers in molecular biosciences"],"pagination":["1128542"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9983363"],"repository":["biostudies-literature"],"pubmed_title":["Preliminary insights on the metabolomics of <i>Trichinella zimbabwensis</i> infection in Sprague Dawley rats using GCxGC-TOF-MS (untargeted approach)."],"pmcid":["PMC9983363"],"pubmed_authors":["Mukaratirwa S","Chaisi M","Ndlovu IS","Silas E","Tshilwane SI","Vosloo A"],"additional_accession":[]},"is_claimable":false,"name":"Preliminary insights on the metabolomics of <i>Trichinella zimbabwensis</i> infection in Sprague Dawley rats using GCxGC-TOF-MS (untargeted approach).","description":"<i>Trichinella</i> infections have been documented globally and have been detected in wild and/or domestic animals except Antarctica. There is paucity of information in the metabolic responses of hosts during <i>Trichinella</i> infections and biomarkers for infection that can be used in the diagnosis of the disease. The current study aimed to apply a non-targeted metabolomic approach to identify <i>Trichinella zimbabwensis</i> biomarkers including metabolic response from sera of infected Sprague-Dawley rats. Fifty-four male Sprague-Dawley rats were randomly assigned into <i>T. zimbabwensis</i> infected group (<i>n</i> = 36) and the non-infected control (<i>n</i> = 18). Results from the study showed that the metabolic signature of <i>T. zimbabwensis</i> infection consists of enriched methyl","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-08-15T03:05:41.875Z","creation":"2025-05-29T16:30:31.952Z"},"accession":"S-EPMC9983363","cross_references":{"pubmed":["36876045"],"doi":["10.3389/fmolb.2023.1128542"]}}