{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wu F"],"funding":["NCI NIH HHS"],"pagination":["251-262"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9987476"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["88(1)"],"pubmed_abstract":["<h4>Background</h4>Epidemiological studies that investigate alterations in gut microbial composition associated with cognitive dysfunction are limited.<h4>Objective</h4>To examine the association between the gut microbiota and subjective memory complaints (SMCs), a self-reported, validated indicator of cognitive dysfunction.<h4>Methods</h4>In this cross-sectional study of 95 older women selected from the New York University Women's Health Study (NYUWHS), we characterized the gut microbial composition using 16S rRNA gene sequencing. We estimated odds ratio (OR) from beta regression which approximates the ratio of mean relative abundances of individual bacterial taxon from phylum to genus levels by binary (2+ versus < 2) and continuous SMCs.<h4>Results</h4>Women reporting 2 or more SMCs had "],"journal":["Journal of Alzheimer's disease : JAD"],"pubmed_title":["Gut Microbiota and Subjective Memory Complaints in Older Women."],"pmcid":["PMC9987476"],"funding_grant_id":["U01 CA182934"],"pubmed_authors":["Afanasyeva Y","Li H","Clendenen TV","Bedi S","Koenig KL","Zhou B","Chen Y","Davey S","Zeleniuch-Jacquotte A","Wu F"],"additional_accession":[]},"is_claimable":false,"name":"Gut Microbiota and Subjective Memory Complaints in Older Women.","description":"<h4>Background</h4>Epidemiological studies that investigate alterations in gut microbial composition associated with cognitive dysfunction are limited.<h4>Objective</h4>To examine the association between the gut microbiota and subjective memory complaints (SMCs), a self-reported, validated indicator of cognitive dysfunction.<h4>Methods</h4>In this cross-sectional study of 95 older women selected from the New York University Women's Health Study (NYUWHS), we characterized the gut microbial composition using 16S rRNA gene sequencing. We estimated odds ratio (OR) from beta regression which approximates the ratio of mean relative abundances of individual bacterial taxon from phylum to genus levels by binary (2+ versus < 2) and continuous SMCs.<h4>Results</h4>Women reporting 2 or more SMCs had ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T00:04:05.253Z","creation":"2025-02-19T02:22:02.87Z"},"accession":"S-EPMC9987476","cross_references":{"pubmed":["35570486"],"doi":["10.3233/JAD-220011","10.3233/jad-220011"]}}