{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(1)"],"submitter":["Pascual J"],"funding":["Lacer S.A."],"pubmed_abstract":["<h4>Background</h4>Many antimicrobial compounds in mouthwashes can have a negative impact on the oral microbiome. O-cymen-5-ol, a compound derived from a phytochemical, has a targeted mode of action and is being used as an alternative. However, its effect on the native oral microbiome is unknown.<h4>Aim</h4>To assess the effect of a mouthwash formulated with o-cymen-5-ol and zinc chloride on the oral microbiome of healthy individuals.<h4>Methods</h4>A mouthwash formulated with o-cymen-5-ol and zinc chloride was administered to a cohort of 51 volunteers for 14 days, while another cohort of 49 volunteers received a placebo. The evolution of the oral microbiome in both groups was analysed using a metataxonomic approach.<h4>Results</h4>Analysis of the oral microbiome showed that the mouthwash "],"journal":["Journal of oral microbiology"],"pagination":["2185962"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9987754"],"repository":["biostudies-literature"],"pubmed_title":["A mouthwash formulated with o-cymen-5-ol and zinc chloride specifically targets potential pathogens without impairing the native oral microbiome in healthy individuals."],"pmcid":["PMC9987754"],"pubmed_authors":["Vivancos Cuadras F","Mira Otal J","Porcar M","Pascual J","Torrent-Silla D","Vilanova C"],"additional_accession":[]},"is_claimable":false,"name":"A mouthwash formulated with o-cymen-5-ol and zinc chloride specifically targets potential pathogens without impairing the native oral microbiome in healthy individuals.","description":"<h4>Background</h4>Many antimicrobial compounds in mouthwashes can have a negative impact on the oral microbiome. O-cymen-5-ol, a compound derived from a phytochemical, has a targeted mode of action and is being used as an alternative. However, its effect on the native oral microbiome is unknown.<h4>Aim</h4>To assess the effect of a mouthwash formulated with o-cymen-5-ol and zinc chloride on the oral microbiome of healthy individuals.<h4>Methods</h4>A mouthwash formulated with o-cymen-5-ol and zinc chloride was administered to a cohort of 51 volunteers for 14 days, while another cohort of 49 volunteers received a placebo. The evolution of the oral microbiome in both groups was analysed using a metataxonomic approach.<h4>Results</h4>Analysis of the oral microbiome showed that the mouthwash ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2026-05-28T11:30:56.014Z","creation":"2025-04-07T03:19:37.557Z"},"accession":"S-EPMC9987754","cross_references":{"pubmed":["36891194"],"doi":["10.1080/20002297.2023.2185962"]}}