biostudies-literatureLanzalaco SAg?ncia de Gesti? d?Ajuts Universitaris i de Recerca3329-3340https://www.ebi.ac.uk/biostudies/studies/S-EPMC9988207biostudies-literatureUnknown8(8)Polypropylene (PP) surgical meshes, with different knitted architectures, were chemically functionalized with gold nanoparticles (AuNPs) and 4-mercaptothiazole (4-MB) to transform their fibers into a surface enhanced Raman scattering (SERS) detectable plastic material. The application of a thin layer of poly[<i>N</i>-isopropylacrylamide-<i>co</i>-<i>N,N'</i>-methylene bis(acrylamide)] (PNIPAAm-<i>co</i>-MBA) graft copolymer, covalently polymerized to the mesh-gold substrate, caused the conversion of the inert plastic into a thermoresponsive material, resulting in the first PP implantable mesh with both SERS and temperature stimulus responses. AuNPs were homogeneously distributed over the PP yarns, offering a clear SERS recognition together with higher PNIPAAm lower critical solution temperACS biomaterials science & engineeringDual-Responsive Polypropylene Meshes Actuating as Thermal and SERS Sensors.PMC99882072017SGR3592021 FI SDUR 2017SGR 00359Gil PAgueda AAleman CArmelin ELanzalaco SMingot JfalseDual-Responsive Polypropylene Meshes Actuating as Thermal and SERS Sensors.Polypropylene (PP) surgical meshes, with different knitted architectures, were chemically functionalized with gold nanoparticles (AuNPs) and 4-mercaptothiazole (4-MB) to transform their fibers into a surface enhanced Raman scattering (SERS) detectable plastic material. The application of a thin layer of poly[<i>N</i>-isopropylacrylamide-<i>co</i>-<i>N,N'</i>-methylene bis(acrylamide)] (PNIPAAm-<i>co</i>-MBA) graft copolymer, covalently polymerized to the mesh-gold substrate, caused the conversion of the inert plastic into a thermoresponsive material, resulting in the first PP implantable mesh with both SERS and temperature stimulus responses. AuNPs were homogeneously distributed over the PP yarns, offering a clear SERS recognition together with higher PNIPAAm lower critical solution temper2022-01-01T00:00:00Z2022 Aug2025-04-21T19:50:27.469Z2025-04-05T17:44:21.069ZS-EPMC99882073565313310.1021/acsbiomaterials.2c00334