biostudies-literatureUnknown11Huang H<h4>Background</h4>Ectopic scrotum (ES) is an extremely rare congenital scrotal malformation. Ectopic scrotum with VATER/VACTERL [vertebral defects (V), anal atresia or anorectal malformations (A), cardiac defects (C), tracheoesophageal fistula with or without esophageal atresia (TE), cardiac defects, renal malformations (R), and limb defects (L)] association is even rarer. There are no uniform guidelines for diagnosis and treatment.<h4>Clinical case</h4>We described a 2-year-5-month-old boy who has ectopic scrotum and penoscrotal transposition and reviewed relevant literature in this report. We performed laparoscopy exploration, rotation flap scrotoplasty, and orchiopexy and achieved a great result during the postoperative follow-up.<h4>Conclusions</h4>Combined with the previous literaturFrontiers in pediatrics1015384https://www.ebi.ac.uk/biostudies/studies/S-EPMC9989158biostudies-literatureEctopic scrotum and penoscrotal transposition: Case report and literature review.PMC9989158Liu XYang HLi ZHuang HLin JXu ZfalseEctopic scrotum and penoscrotal transposition: Case report and literature review.<h4>Background</h4>Ectopic scrotum (ES) is an extremely rare congenital scrotal malformation. Ectopic scrotum with VATER/VACTERL [vertebral defects (V), anal atresia or anorectal malformations (A), cardiac defects (C), tracheoesophageal fistula with or without esophageal atresia (TE), cardiac defects, renal malformations (R), and limb defects (L)] association is even rarer. There are no uniform guidelines for diagnosis and treatment.<h4>Clinical case</h4>We described a 2-year-5-month-old boy who has ectopic scrotum and penoscrotal transposition and reviewed relevant literature in this report. We performed laparoscopy exploration, rotation flap scrotoplasty, and orchiopexy and achieved a great result during the postoperative follow-up.<h4>Conclusions</h4>Combined with the previous literatur2023-01-01T00:00:00Z20232025-04-05T14:16:44.841Z2025-02-19T04:44:04.809ZS-EPMC99891583689640710.3389/fped.2023.1015384