{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["161(3)"],"submitter":["Potthoff AL"],"funding":["Universitätsklinikum Bonn"],"pubmed_abstract":["<h4>Purpose</h4>Patients with brain metastasis (BM) from solid tumors are in an advanced stage of cancer. BM may occur during a known oncological disease (metachronous BM) or be the primary manifestation of previously unknown cancer (synchronous BM). The time of diagnosis might decisively impact patient prognosis and further treatment stratification. In the present study, we analyzed the prognostic impact of synchronous versus (vs.) metachronous BM occurrence following resection of BM.<h4>Methods</h4>Between 2013 and 2018, 353 patients had undergone surgical therapy for BM at the authors' neuro-oncological center. Survival stratification calculated from the day of neurosurgical resection was performed for synchronous vs. metachronous BM diagnosis.<h4>Results</h4>Non-small-cell lung carcino"],"journal":["Journal of neuro-oncology"],"pagination":["539-545"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9992001"],"repository":["biostudies-literature"],"pubmed_title":["Survival after resection of brain metastasis: impact of synchronous versus metachronous metastatic disease."],"pmcid":["PMC9992001"],"pubmed_authors":["Borger V","Ilic I","Radbruch A","Heimann M","Lehmann F","Schuss P","Vatter H","Schafer N","Herrlinger U","Schneider M","Paech D","Potthoff AL"],"additional_accession":[]},"is_claimable":false,"name":"Survival after resection of brain metastasis: impact of synchronous versus metachronous metastatic disease.","description":"<h4>Purpose</h4>Patients with brain metastasis (BM) from solid tumors are in an advanced stage of cancer. BM may occur during a known oncological disease (metachronous BM) or be the primary manifestation of previously unknown cancer (synchronous BM). The time of diagnosis might decisively impact patient prognosis and further treatment stratification. In the present study, we analyzed the prognostic impact of synchronous versus (vs.) metachronous BM occurrence following resection of BM.<h4>Methods</h4>Between 2013 and 2018, 353 patients had undergone surgical therapy for BM at the authors' neuro-oncological center. Survival stratification calculated from the day of neurosurgical resection was performed for synchronous vs. metachronous BM diagnosis.<h4>Results</h4>Non-small-cell lung carcino","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-22T13:07:52.505Z","creation":"2025-04-06T00:33:15.121Z"},"accession":"S-EPMC9992001","cross_references":{"pubmed":["36695975"],"doi":["10.1007/s11060-023-04242-5"]}}