biostudies-literaturePerez NBNCATS NIH HHSNINR NIH HHS93-102https://www.ebi.ac.uk/biostudies/studies/S-EPMC9992148biostudies-literatureUnknown72(2)<h4>Background</h4>Depression is a growing global problem with significant individual and societal costs. Despite their consequences, depressive symptoms are poorly recognized and undertreated because wide variation in symptom presentation limits clinical identification-particularly among African American (AA) women-an understudied population at an increased risk of health inequity.<h4>Objectives</h4>The aims of this study were to explore depressive symptom phenotypes among AA women and examine associations with epigenetic, cardiometabolic, and psychosocial factors.<h4>Methods</h4>This cross-sectional, retrospective analysis included self-reported Black/AA mothers from the Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure study (data collected in 2015-2020). CNursing researchLatent Class Analysis of Depressive Symptom Phenotypes Among Black/African American Mothers.PMC9992148R01 NR013520TL1 TR001447Perez NBD'Eramo Melkus GSun YVVorderstrasse AATaylor JYYu GCrusto CAWright FfalseLatent Class Analysis of Depressive Symptom Phenotypes Among Black/African American Mothers.<h4>Background</h4>Depression is a growing global problem with significant individual and societal costs. Despite their consequences, depressive symptoms are poorly recognized and undertreated because wide variation in symptom presentation limits clinical identification-particularly among African American (AA) women-an understudied population at an increased risk of health inequity.<h4>Objectives</h4>The aims of this study were to explore depressive symptom phenotypes among AA women and examine associations with epigenetic, cardiometabolic, and psychosocial factors.<h4>Methods</h4>This cross-sectional, retrospective analysis included self-reported Black/AA mothers from the Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure study (data collected in 2015-2020). C2023-01-01T00:00:00Z2023 Mar-Apr 012025-04-04T03:00:31.514Z2025-04-04T03:00:31.514ZS-EPMC99921483672977110.1097/NNR.000000000000063510.1097/nnr.0000000000000635