biostudies-otherUnknown5Matthew RobertsCPT: pharmacometrics & systems pharmacology554-564Homo sapienshttps://www.ebi.ac.uk/biostudies/studies/MODEL1807180004biostudies-other27647667Matthew RobertsfalseHartmann2016 - Blood coagulation model for simulating anticoagulantsMathematical model of blood coagulation. Reused Wajima2009 model with modifications to reactions 27 (formation of Va:Xa complex), 32 (Xa inhibition by TFPI) and 45 (Xa inhibition by TFPI-Heparin complex) as described in publication equations 2,3 and 4. Publication lists parameter sets to simulate Rivaroxaban, VKA and Enoxaparin (supplementary files).2018-07-18T00:00:00Z2025-07-14T17:51:41.329Z2025-03-30T22:43:34.956ZMODEL1807180004BIOMD0000000340SBO:0000048SBO:0000038SBO:0000035SBO:000003627647667CHEBI:28304CHEBI:10033CHEBI:28384GO:0030193GO:00075969606P02671P03951P03952P10646P13726P12259P08709P00747P04070P00748P00734P05160P01008P02679P00488P00742P00740P02675P00451P07204P07225