biostudies-otherUnknown8Matthew RobertsJournal of thrombosis and haemostasis : JTH1745-1753Homo sapienshttps://www.ebi.ac.uk/biostudies/studies/MODEL1807240001biostudies-other20492473Matthew RobertsfalseOrfeo2010 - Simulating the effects of fondaparinux and Rivaroxaban on thrombin generationReused mathematical model (Hockin et al., 2002) of blood coagulation simulating the effects of coagulation factor inhibitors, fondaparinux (synthetic heparin) and Rivaroxaban. Fondaparinux (Fpx) simulated to reversibly bind with ATIII before irreversibly binding to Xa, IXa, mIIa, TF:VIIa, Xa:Va and IIa. Rivaroxaban simulated to bind reversibly to Xa and Xa:Va.2018-07-24T00:00:00Z2025-07-14T17:51:27.072Z2025-03-30T22:43:49.18ZMODEL1807240001SBO:0000039SBO:0000038SBO:0000035SBO:0000036BIOMD000000033520492473D07086CHEBI:61033CHEBI:68579GO:0007596D018449606BTO:0000131P10646P00734P13726P12259P01008P08709P00742P00740P00451