{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Lucian Smith"],"journal":["BMC systems biology"],"pagination":["57"],"species":["Mus musculus"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL1903040001"],"repository":["biostudies-other"],"additional_accession":["28521769"],"pubmed_authors":["Krishna Kumar Tiwari","Lucian Smith"]},"is_claimable":false,"name":"Mouse Iron Distribution - Rich and Deficient iron diets (tracer)","description":"

Mouse Iron Distribution Dynamics

Dynamic model of iron distribution in mice. This model attempts to fit the radioiron tracer data from Lopes et al. 2010 for mice fed iron deficient and rich diets by adjusting the rate of iron intake (vDiet) and the hepcidin synthesis rate (vhepcidin) independently for each experiment. All other parameters are those that provide the best fit for the adequate diet.

This model includes the radioiron tracer species.

Differences in parameter values between deficient, rich, and adequate diets:

Diet	vDiet	v_hepcidin
Adequate	0.00377422	1.7393e-08
Deficient	0	8.54927e-09
Rich	0.00415624	2.30942e-08

","dates":{"release":"2019-03-04T00:00:00Z","modification":"2025-07-15T09:54:08.707Z","creation":"2025-03-29T20:55:03.099Z"},"accession":"MODEL1903040001","cross_references":{"biomodels___db":["BIOMD0000000734"],"pubmed":["20704761","28521769"],"ncit":["C61408","C15222","C25559","C75947"],"chebi":["CHEBI:24875","CHEBI:29034"],"mamo":["MAMO_0000046"],"go":["GO:0055072","GO:0006826","GO:0005488"],"taxonomy":["10090"],"bto":["BTO:0000141","BTO:0000131","BTO:0000365","BTO:0000424","BTO:0001281","BTO:0000759"],"uniprot":["Q921I1","Q9EQ21"]}}