{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Lucian Smith"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL1903280002"],"repository":["biostudies-other"],"additional_accession":["10.1073/pnas.1816000116"],"pubmed_authors":["Mohammad Umer Sharif Shohan","Lucian Smith","Simon Mitchell"]},"is_claimable":false,"name":"Simon2019 - NIK-dependent p100 processing into p52, Mass Action, SBML 2v4","description":"

This model represents NIK-dependent p100 processing into p52 with mass action kinetics. While this model shows identical dose-response to the Michaelis-Menten representation, when IkBd degradation is included the dose-response is no longer monotonic in mass action models due to substrate complex competition.

","dates":{"release":"2019-03-28T00:00:00Z","modification":"2025-07-15T09:49:06.974Z","creation":"2025-03-29T21:58:55.317Z"},"accession":"MODEL1903280002","cross_references":{"biomodels___db":["BIOMD0000000868"],"pubmed":["31048505"],"ensembl":["ENSG00000077150"],"ncit":["NCIT:C18888","C61559"],"mamo":["MAMO_0000046"],"go":["GO:0003729","GO:0006397"],"uniprot":["Q00653","Q99558"],"doi":["10.1073/pnas.1816000116"]}}